Address for correspondence: Miroslaw Dluzniewski, MD, PhD, Medical Center of Postgraduate Education, ul. Poznańska 22, 00–685 Warszawa, Poland, tel: +48 22 525 12 63, e-mail: miroslaw.dluzniewski@cmkp.edu.pl
Received: 26.06.2019 Accepted: 1.10.2019
Acute limb ischemia due to intracardiac myxoma in a patient with atrial fibrillation
Anna Szymanska
1, Joanna Syska-Suminska
1, Jerzy Rekosz
1, Anna Skrobisz
1, Anna E. Platek
2, Miroslaw Dluzniewski
11Department of Heart Diseases, The Medial Center of Postgraduate Education, Warsaw, Poland
2Department of General and Experimental Pathology with Center for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Poland
An 82-year-old female with a history of par- oxysmal atrial fibrillation was hospitalized due to exertional dyspnea which had lasted for 2 weeks, with no peripheral edemas. The transthoracic echocardiography (TTE) revealed a mass in the left atrium (1.6 × 2.2 cm) with connective tissue peduncle attached in the area of fossa ovalis in the intraarterial septum (Fig. 1A, B). The transesopha- geal echocardiography (TEE) confirmed mobile mass in the left atrium suggesting atrial myxoma (Fig. 1C). Cardiac myxoma removal was offered to the patient, but the patient did not agree to the procedure and was discharged.
Twenty hours after the discharge, the patient presented again in the Emergency Room due to pulmonary edema in the course of rapid atrial fi- brillation and symptoms of acute left limb ischemia (no femoral arterial pulse, coldness, cyanosis, and paralysis). TTE showed no myxoma mass in the left atrium. Only connective tissue peduncle remained in the area of fossa ovalis in the intraarterial sep-
tum (Fig. 1D, E). Vascular ultrasonography was performed and demonstrated complete occlusion of the left femoral artery. The mass was recovered via percutaneous intervention and examination confirmed it to be myxoma. Revascularization was provided immediately and ensured no vascular or neurological defects. Subsequent TEE revealed a small residue of connective tissue peduncle in the area of fossa ovalis (Fig. 1F). The patient was discharged without complications.
Myxomas can manifest in miscellaneous ways.
This might include a fever of unknown origin, acute myocardial infarction, stroke, paraneoplastic effects (including vasculitis, hematological changes, con- stitutional symptoms). While ischemic symptoms are relatively frequent, they are more often associ- ated with a blood clot mobilization. Tumor emboli- zation in peripheral limb circulation is extremely rare. Nevertheless, myxomas must be kept in mind as one of the probable causes of thromboembolic complications in various vascular sites.
Conflict of interest: None declared CLINICAL CARDIOLOGY
Cardiology Journal 2019, Vol. 26, No. 6, 806–807
DOI: 10.5603/CJ.2019.0121 Copyright © 2019 Via Medica
ISSN 1897–5593
806 www.cardiologyjournal.org
IMAGE IN CARDIOVASCULAR MEDICINE
Figure 1. The echocardiography studies; A. Transthoracic echocardiography (TTE) on admission — parasternal long axis view; B. Transesophageal echocardiography (TEE) on admission — 4-chamber apical view; C. TEE on admission;
D. TTE after vascular intervention — parasternal long axis view; E. TTE after vascular intervention — 4-chamber apical view; F. TEE after vascular intervention.
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Anna Szymanska et al., Limb ischemia due to myxoma