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IMAGES IN CARDIOLOGY

Cardiology Journal 2011, Vol. 18, No. 1, pp. 92–93 Copyright © 2011 Via Medica ISSN 1897–5593

92 www.cardiologyjournal.org

Address for correspondence: Can Yücel Karabay, Kartal Kosuyolu Heart and Research Hospital Cardiology, Istanbul, Turkey, tel: +90 0505 95 77 872, fax: +90 216 45 96 321, e-mail: karabaymd@yahoo.com

Received: 04.04.2010 Accepted: 27.04.2010

A failed case of percutaneous septal closure of fenestrated atrial septal defect

Can Yucel Karabay, Akin Izgi, Cihan Dundar, Soe Moe Aung, Altug Tuncer, Cevat Kirma

Kartal Kosuyolu Heart and Research Hospital Cardiology, Istanbul, Turkey

Abstract

A patient presenting with a history of palpitation and exertional dyspnea was initially diag- nosed with two separate secundum-type atrial septal defects by transesophageal echocardio- graphy. Subsequent transesophageal echocardiography, after failure of closure with two sepa- rate closure devices, showed another defect and an ongoing left to right shunt. During surgery, more defects were observed. The defects were successfully repaired using pericardial patch without incident. (Cardiol J 2011; 18, 1: 92–93)

Key words: percutaneous closure of fenestrated atrial septal defects

Introduction

Atrial septal defects (ASD) represent about 10% of all congenital cardiac anomalies [1]. Percu- taneous closure of secundum-type atrial septal de- fects is a safe and effective alternative to surgical closure [2]. The use of a closure device in multiple and large defects is still controversial [3]. Studies concentrating on the better evaluation of septum have been conducted in order to increase the suc- cess of the procedure. In our case, after the closure of two separate defects detected by transesopha- geal echocardiography (TEE) with two devices, an ongoing left to right shunt was seen, and surgical treatment was decided. We present a case of per- cutaneous closure of fenestrated ASD.

Case report

A 31 year-old woman was admitted to our hos- pital with palpitations and exertional dyspnea. At presentation, her electrocardiogram showed incom- plete right bundle branch block and sinus tachycar- dia. Transthoracic echocardiography revealed atrial septal defect and mild right ventricular enlarge-

ment with elevated pulmonary artery systolic pres- sure (45 mm Hg). For evaluation of rim sufficien- cy, TEE was performed. Transesophageal echocar- diography revealed two separate defects at the sep- tum (Fig. 1). In addition, aortic and posterior rims were 6 and 7 mm, respectively. Accordingly, we planned percutaneous septal closure, to be per- formed the next day. Firstly, a 10.5 mm occluder was applied after balloon sizing of the defect (Fig. 2A), and subsequently a second 12 mm occluder was placed (Fig. 2B). After this step, we detected an- other defect and an ongoing left to right shunt by TTE. Thus, we removed both devices without any complication and decided on surgical treatment. In the operating room, we detected four different de- fects at atrial septum (Fig. 3). The defects were then fully repaired using a pericardial patch. The post-operative course of the patient was unevent- ful, and she was discharged on the fourth post-op- erative day.

Discussion

Atrial septal defects represent about 10% of all congenital cardiac anomalies [1]. Percutaneous

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93 Can Yucel Karabay et al., Fenestrated atrial septal defect 

www.cardiologyjournal.org

closure using occluder devices has become a popu- lar, effective, and safe method of treatment of se- cundum ASDs in spite of years of successful surgi- cal experience [2].

The TEE is the cornerstone for evaluation of rim sufficiency and guidance of closure procedure.

In the presence of more than one defect, measure- ment of the distance in between should be done, and a single device is suggested for a distance of less than 7 mm. When the distance is more than 7 mm, two separate devices should be applied [4]. Recent studies have made use of advanced echocardiogra- phy such as real-time 3D echocardiogram in order to evaluate interatrial septum better, thus increas- ing procedural success [5]. In our case, although TEE had detected two separate defects, a left to right shunt persisted after the closure, and the devices were subsequently removed.

This case, as well as current literature, sug- gests that the use of advanced imaging techniques for better evaluation of interatrial septum may increase the success of percutaneous closures.

Acknowledgements

The authors do not report any conflict of inte- rest regarding this work.

References

1. Hoffman JE, Christianson R. Congenital heart disease in a co- hort of 19,502 births with long term follow up. Am J Cardiol, 1978; 42: 641–647.

2. Du ZD, Hijazi ZM, Kleinman CS, Silverman NH, Larntz K. Com- parison between transcatheter and surgical closure of secundum atrial septal defect in children and adults. J Am Coll Cardiol, 2002; 39: 1836–1844.

3. McGarvey J, Ota T, Anderson W, Katz W, Zenati MA. Highly fenestrated septum primum leads to failure of Amplatzer septal defect closure. Ann Thorac Surg, 2008; 86: 998–1000.

4. Awad SM, Garay FF, Cao QL, Hijazi ZM. Multiple Amplatzer septal occluder devices for multiple atrial communications: Im- mediate and long-term follow-up results. Catheter Cardiovasc Interv, 2007; 70: 265–273.

5. Balzer J, van Hall S, Rassaf T et al. Feasibility, safety, and efficacy of real-time three-dimensional transoesophageal echocardiogra- phy for guiding device closure of interatrial communications:

Initial clinical experience and impact on radiation exposure. Eur J Echocardiogr, 2010; 11: 1–8.

Figure 2. A: 10.5 mm occluder was performed (arrow);

B: 12 mm occluder was performed (arrow).

A B

Figure 3. Four different defects at atrial septum.

Figure 1. Transesophageal echocardiography revealed two different defects at the septum (arrows).

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