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Delft University of Technology

Towards a flexible brain implant with 10.000 independent channels

Hosman, T.B.; Serdijn, W.A.; Giagka, Vasiliki

Publication date 2019

Document Version

Accepted author manuscript Citation (APA)

Hosman, T. B., Serdijn, W. A., & Giagka, V. (2019). Towards a flexible brain implant with 10.000 independent channels. Abstract from ProRISC 2019, Delft, Netherlands.

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Towards a flexible brain implant

with 10.000 independent channels

Timothy Benjamin Hosman

1,2

, Wouter Serdijn

1

, Vasiliki Giagka

1,2

1Bioelectronics Section, Department of Microelectronics, Delft University of Technology, Mekelweg 4, 2628 CD, Delft, The Netherlands

2Technologies for Bioelectronics Group, Department of System Integration and Interconnection Tech-nologies, Fraunhofer Institute for Reliability and Microintegration IZM, Berlin, Germany

E-mail: tim.hosman@izm.fraunhofer.de

ABSTRACT

Electronic implants are becoming a valuable tool to explore as well as regulate neural activity, potentially overcoming neural disabilities that are not yet curable. For effective exploration and regulation, it has become increasingly necessary to cover larger areas of neural tissue and to inter-act at a higher resolution by means of electrode arrays. Application specific integrated circuits (ASICs) are often employed to accommodate the interaction with these electrodes but these are limited in size, which consequently limits the amount of individual recording or stimulation chan-nels. The de facto solution that allows for the connection of an electrode array to an ASIC is to multiplex high numbers of electrodes to a single ASIC channel. However, due to switching and signal latencies only a limited number of electrodes can be multiplexed per channel. Multiple chan-nels on an ASIC are therefore desirable to accommodate implants with a high electrode count. Due to recent miniaturization advances, an ever-increasing number of channels can be made avail-able on a single ASIC and the urgency arises to investigate technological complications of connect-ing these channels to electrodes. In this work we will investigate the technological complications of assembling a flexible electrode array substrate to an ASIC with a high number of independent channels. Our aim is to manufacture a biocompatible multi-layer substrate-ASIC assembly that can route 10.000 independent recording and/or stimulating sites to an array of electrodes covering a large area of the brain.

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