Nieinwazyjna ocena parametrów naczyniowych i funkcji śródbłonka u pacjentów z hipercholesterolemią rodzinną

Pełen tekst

(1). c. 012356718

(2)

(3) . !"#!$%&'%(!#"#)!!*+,#!-%(./0",1 +!$#'(!1)$%#)"23'%"2&4!%".41. 556667689:;<1=>:29:5676?2@ AB

(4) ABC DEFGFHFEI1JE1KLMN1ON1GPJN1QLE#!R%+#)0S!$%"*T!.T!RUV.1. W XY XZ X Z [>6=82<\7<7158]919^1>]6_7]. [>6=82àbb.

(5) . . . . . 3456789 9

(6) 4 5

(7) 7 99

(8) 5 9479 9479 7

(9)

(10) 96. !"#$%&'()*+,-./.(0'/.12)345426.-728930)5:(;<2428930)5:(;-5=02>9.?9(492@04'0:92@5=-0./A.5=0&. . . BCDEFGHGIJCKLCFMKGIECHMLGNGIHIFGOGPQIEFCRSKLTUV W XYZ[\]^W_^àYbcWdeZf`\gahieWeWj^kl^èZWmen^Yko\p^ga^Y\p^ceeWq\rle``^[W V sFCRSKLIHMEtNuvwGwMCHGwxIEFDSDIywvzI{TFCESRMK|IV }V~ V }V}VVV VVVVV VV. . . ¡¢£¤¥¦§¨£§©¨¨¡ª£¤¥¦« ¬¨ª¦¢®¥¦¯°§ª§±£²³§´µ²°²¶¡·¸«. 0.

(11) 3456789 8

(12) . !"#$%&'()*+,-.' /0-))1-23)4-30' 5#6'7 87'95:87'; <68!7'' =>?@ABC@?>DEF?GHI .

(13) . 0.

(14) 34567894

(15) 7 . H. . !"#$!%&'()&%&*+,"%-+#&*+.%$-/"0( 1"2(3&4566767889:6;<=4:> ?4;:@9A94A=4 !"#$!%&'()&%&*+B#C%1(2&*+DE#F+(*+-1&*+G 48@;=5678989:6> IJKLMNOLKJPQRKSTUH H 0.

(16) 23426789 4

(17) . 9 48262 276

(18) . 263

(19) !"!#$%&'()*+,'-.'(+,'/%0(+12%330 -.("4 !"!"!#50.+/')*03%2/*%&'()*+,'-.'(+,'/%%(+12%33'6 -.("4 !"!"7#89(02:,%3%)23;*%&'()*+,'-.'(+,'/%%(+12%33'6 -.("!7 !"!"<#=+2&+2303%'*%&'()*+,'-.'(+,'/%%(+12%33'6 -.("!> !"!">#?2;33%:%(;2;:0@*%&'()*+,'-.'(+,'/%%(+12%33'6 -.("!A !"7# BCDEFGHIJKLIMNOPIQHRP -.("!S !"7"!#TUEHRMLQLVUIKNWMLXCDEFGHIKM -.("!S !"7"7#YPZVUIKNWMLXCDEFGHIKM -.("![ !"<# \%'%3@02;63'/'.+1;+)'3;]ÎKNWQLXCDEFGHIKMLQL_MCM`JaCDR 30)2;3%+@;)* -.("77 !"<"!#b02+1;,0.0)60acaIQNPLCM`Q'33'6%31^:+@0303%'1+:(@%'3%'/ -.("7> !"<"7#d'.+1;+)'3;ZOaPRIHXNQLacaIQN%]0,%acaIM -.("7S 8efgh

(20) ii j6874k4j86g

(21) il <"!# m(^&0901030 -.("<> <"7# n')*3%:0RPKHIPRMIQMLFMEMoLIMNOPIQHRPNp -.("<q <"7"!#rNJIMLRMOHEPsMaMNWQLacaIQNPLCM`QJIIJWLQIEUKHRMIJW 3%'1+:(@%'3%'/HCMOL_HELR_GPRJ`LJtOHtJIIQJL_HEMIJWL 3%.(+u,%)'(;3; -.("<q <"7"7#rNJIMLZOaPRIHXNQLacaIQN&(2;&+/+);/'.+1;vwxyz{|}~ -.("> <"7"<#IMsQOMLVMsQLacaIML_COPL_H`HNPLVHaH_sJaPO`HtCMVU -.(">7 <"7">#rNJIML_HRaMCOMsIHXNQLRPKHCOPZaMIPNpL`JaHE -.(">> <"<# 30,%20-.0.;-.;)230 -.(">q

(22) l >"!# ?*0(0:.'(;-.;:090103'6u(^&; -.(">A >"7# 8)'30@02+EPsMaMNWQLacaIQNPLCM`QJIIJWLQIEUKHRMIJWLIQJEHKCRQJIQJ` -.(">[ >"<# rNJIMLVMsQLacaIML_COPL_H`HNPL`JaHEPLvwxyz{|}~ -.("q! >"># rNJIMLVMsQLacaIML_COPL_H`HNPLVHaH_sJaPO`HtCMVU -.("qq . 0.

(23) 234 6789

(24) 897

(25) 97 9 8 ! "

(26) #97 9 7

(27) 9#8! ! ! ! ! ! 23( )#

(28) 9* +,-.&/,$%01,23!45%.6! ! ! ! 23(38)#

(29) 9* 9:;!.&0/!45%.6,!<=>?@ABCDEF F 23(37)#

(30) 9* 8 8

(31) G 7

(32) 98! ! IJK LMNOPNQRSS S S S S S S IXJK YZ[\]^Z_àbcd_eabfg_dbdhiXjNOXSS S IXXJK NmnoNpqpoiXoSS S S S S S IXXXJKYbs^bcaabtu_ZSS S S S S S XwJK RioONMS S S S S S S S S S S S S S S S S S S S S S S S S S S S S S S . 0. ! ! F ! S S S S S. $%&3!4'! $%&3!(7! $%&3!(7! $%&3!(H! TUVJSWWS TUVJSklS TUVJSlrS TUVJSlvS TUVSJxkS.

(33) 23456859 6

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` D9:5_76:2/135071>.6275.K8a QXY*b 41:54752;-371/B7:01D529K8\:1>Z2@54620=075 b D9:5_76:29K08D71>.62\-05 Mc L13BC2d1B7<5 [N D9:5_76:2DKL1.76-765 . 0.

(35) 23 56789. 3

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àbacdefgdhijklmndelofopfmiljkqL )021'32#($>#,">)/*#6/0@"#.0>#,#66$A'+30#17A.*3B#'#*'%+3'#.'#A*+/*.0K 06A06*@0/$32+*#3*)5+/4)5#.0*/'(','A'32+';#rFEG8HsESZINKH8GIGEMKMQF9CO EQTtSHPEG98KMGuvlijvi,"%'/'A0B#>*#5#,25!'#(/04%0#EtKC8OR89QEGHKFJCD8H *6'5+"57,#*+*65@#!0*/*#6()5',,"#$(/0'&#,#@*5'!A0/@0*#+A*)5*A$UwWX x96'+4#52Gyz{|#%$#5/"@'A0#}'1(4#}!A';#YENOREZPFOCHTTZEGEZ8HE8EL >*,&':.0*#!'%#A$!#!.0>.'#'%5",.:[#5"+>*#*+*657,#6,($3*#6'5A10+/.0*# GOIEPHK)54>*.0'#+A*)5*A$#,*#%,0;#~+/*.0*#5#,")546$32+*# (/0..0*# H$,'$.%,'.*#1*.*5"+/.0*#.'/,'.#06*+A*)5*A*@02#(/0..2#cdleled loipv feikmipfeinqUWX !)*,'+3*#,0*A$#66$A'+30#,)%'/$32B#>*#HQKFCDESKINKFESKRH9FEZJH889ZENOP9 %&#;#66$A'+30#17A.*3;#}'#:,0*+0*#>"3*#%&#y#@0A0.7,#A$(/0#!+02>."+D 06*+A*)5*A*@02#(/0..2;#~/'+$3*#)04B#>*GYESICKA0+/!'#+"+#@>*#)041'[# EZ ¡ZEy¢#5")04+"U£WX . 0.

(37) 2356789

(38) 9 9!"#$!!

(39) %! 9 9

(40) & '.

(41) ! !9!(9 99( )9*&+,,-./,

(42) 0 1234 ! !99( )9*&5///,,,

(43) 0"6 %7 %!'8 %$%!$

(44)

(45) !

(46)

(47) $!9$$9 9

(48) 9!9

(49) 9

(50) (

(51) " 93(:;<62=:1>678621>6?;;21@4;AA65@4;6@4;=41A653B8171?3>A;6 9 9()9?B83=53C6AB@>326=6<8123=:1>678621>BDED FGHGIJIKLMNKOPQRSTUKLSVMVWMTPSQRKWPXPVTMWY8$

(52) ! 9!9 %7!9!

(53) !=:1>678621>DEDZ[B83=5383<1\1@B5643]B246A;6^BA_=5;>B]4?A;65746A;6 9 !!9 %

(54) 9

(55) ` 9

(56) ! !9Y 9 7!

(57) $ FB:1?14aC18b=1 %

(58) 6\a=:\a8a\3A;6;823A7<128=:1>678621>BDED $

(59) $

(60) !" c6=6<812a=:1>678621>BDED4(

(61) 9 9! \67( 9 $

(62) !!9

(63) !9! !9 7 !$

(64) $ 7$ $

(65) !"d 79

(66) 9

(67) =:1>678621>6?DED56781AA3@21@466A@1=a814a 9 7! $

(68) $

(69) $7! 9 "#$ >65Aa?683<;6=:1>678621>

(70) 9! 9! !$

(71) $"e9

(72) !

(73) $789

(74) 9 A3565

(75) 9 (Zf381?;3787!9

(76) $

(77) $ $! )' 26@B_834a3[g-h1iFWPOjkTlmlKnIoUOWMkRUInIpPTULMqLjTlWULMIkMPQmUpjKrb6A4a?B

(78) 9 !(6A@1C6AA6C1=:1>678621>BZs1A3@81>;=4]3GHGIJ A3<1\;624=:A;:6<381=a83567826CB>1\3A34C1@A;

(79) $

(80) $ A3=:1>678621>tuvZha_>86A7=:6?38a=4A;6B_34B56ca=;A35Z . . 0.

(81) . 456789

(82) 696596 !"78#$%8& '9(77956(79)*+, -./01.23.14.1.56772893 :;/ 0<=/82>34/?1;0@>.A2?AB; 2 1/.2C-CD

(83) EF9.G .5E:3A;5.>32 1/.2<0=/:;/ 01.>.5;0@< :.901.5EFHIJ9K8J6L89856<=/8212E54/>M9N9 OPQRQS Z[W\Q]Y^TSTUVQWXYS_[W[`Va_QS bc[dVSc[]aVeàfeS TUVQWXYS. &96L9ghii %9J69klk897m687 jA;2E43/E3A=69 9659 +. . n=28 A=<12>5.> o5.02E3F;A12>5.>3 4=5A=69 6klk897m687 9659. 01. .

(84) 2 7 = ?. 456789

(85) 98 68 97 6 7 ,-%8678 ./8/87 0 ! 12 6

(86) "#$!%&!'(!)!*+ 3'4!%%-56 ,-%8%!* ;!*$#-%'6<'& %&*%)!%&!"$ 3'*-%!)'6-'8< /57 1 99 75/968:8 7 /57 8/87 012 6

(87) ,-%4!%!* >5!)!*< "$86# 86

(88) 9 /: ,-%

(89) 9 6 8/87 6 @!*!"$ &*%)!%&!"$ /57 1 99 75/968:8 7 /57 A /57 1 99 75/968:8 7 /57 B82

(90) / /57 1 998. C D81 EAF1 59G7 /8/87 HBHI?JA K*$L!L-8*-6%)M654*'N9G7 /85< $!LN5#OPOQRS286GTUVWXYUVZ[UVU\V]^[_`Wa286GbcdefXU\VU\V]^[_` gV_h^\]Yi^ìjk][Z[i[_lm^n[_`]oU^`faAB /:1 D8/68 6 751. 8

(91) 899G7 / 286GTUVWAp6)4#'%8*%$-*$30qrr!%48*!%!s>s %%!%"#%)4!8%$4!%8&!%48*!%'s>s!*+t%$

(92) 78 5 689G7 /8286Gbcdef#)4%8*'*$! 78 958565 .

(93) 68989786286Au 1.

(94)

(95) 9 99689 681/9D5OPOQR` :8 7 /5/8 .G78./982 9 7 9 9/: 1878 1GHBHG /5.IvJA w!L4!L'*$8*$!%4L!L-8*-6%)84#N<N!6&%$ /867 9 6 87 9 /:8

(96) 68

(97) 965 7 6G'88)")<'-!%$!L+ x8**$%#8&#8*-M'$!L%-N!6&%$*$899G7 / %66-<8#!$'$%$'6%!%85$8*4!L"$ (!)$!L'(8!06 /956 5/:A y8/: 1878 -6%8'*-5%8*D 98z{|{X}_Z[_^` ~^_^Z[Y_`_]^\[]Y_g^`[_`~Y_a)' qr+!L-&"!46N6$ 8*%MN)8**/: D 8

(98) 6 286

(99) 98

(100) 9/9 6 88<"#*86-$ 6#)4!$#))N6-'#-5-N4 . 00.

(101) 456789

(102) 5 8 6 47 6 !" 456789

(103) 5 #$%&' 8 6 47 6 ( (" 456789

(104) 5 )*+,- 8 6 47 .!." /01 234536789:69:;<6=>?9:37<67<?@:ABCD5E34BF5;:AB48B;9;:>GBH9369IBH< >=J7BD869KB: L ML 8 L7NO N OL95 O NL8O F9KB:AIB>93<:;8=ECE5>BD9KBP: 7 L 34>49KQHFBR>8:>GBIBS5:D89T>BD9?U . VWVWXYZ[\]^_àbcbd^ce_fbgh\dfiahjkh\iahlbb_\im^bcchn_ _ 23AQHF@:>G=I=769I5365>4F@:>9>G@:CH=:D3453678>G:;<6=>?8:ABDBC<?@>5>G: G8A9I>GBH9369IBH9;8o:IBC48FF@:?936:4F=>4F89:ABCD5E34BF5:AB48B; 8 6 5 >=J7BD869KB:8:8 6 5 pp L 5L8 MLq 2=G=:38o:BF:4=4D5>4=?:D:KI=F8>=>G: N rss N tss 4

(105) N 5 6 O

(106) 6 7 5 4O

(107) 6 N uss N vsss 4

(108) Nq wL7OO 6 45 O7OL8O79 I=D8CJBD5:AB48B;:6IQ?KH8>9I5CQDU:2I=4:4:;<6=>?=;8:ABDBC<?@>5;8: G8A9I>GBH9369IBH9;8o: IBC48FF@ D3AQJD536oABD=x: ;BK@: 8O7 4 6=7E9: 69P: 76QI9 ABDBC<?@:G8A9I6I8KH8>9I5C9;8oU:2:4D8@47<:4:65; AB48B;:6IQ?KH8>9I5CQD:;BE9: S5x:IQDF89E:ABCD5E34BF5U:yBF=C6B =F=H84<?@8 N

(109) 74 88 8O7 4 474 N 8O 7 QDF89E:4:BSF8EBF5;:AB48B;9;:8 6 5 !p z'{|}{'~|' |$%$ %|" /1q w7M LM O4 76

(110) 8 7M89 >GBH9369IBH<:;=:CH=:A=>?9F6QD: ABD=EF9:8;AH87=>?9:7H8F8>4F9U:yIB>93:;8=ECE5>BD5:?936:O 78O O O 8 LN59 >4o36B:AI49CD>493F@:>GBIBSo:F89CB7ID89FF@:39I>=U 3BS=:BS>8@EBF= ! ;=::AI=DCBABCBS89T36DB:4=>GBIBD=F8=:F=:B36I5:493AQJ:D89T>BD5 O N ts M 4 E5>8=U 8A9I>GBH9369IBH9;8=:IBC48FF=:6B:AI49C9:D3453678;:AIB>93:;8=ECE5>L CB657=?@>5:F=>45F8=:D89T>BD9P:I4=C489?:4=R:6o6F8>9:BSDBCBD9:8:;Q4KBD9U:yI49S89K: M 8O 8 6 4 NO 9 4NML7 9 6 NN76ML L 47 4 8O M74

(111). 68O 4 4 678O 4 7O RIBCBD837BD5;8 /1q yBC7I9RH=:38o:6<:AI49C9:D3453678;:4F=>49F89:A=H9F8=:656BF8<:BI=4:D3AQJ836F89F8=: ><7I45>5:8:F=C>8RF89F8=:6o6F8>49KBU . 01.

(112) 3456789 6

(113) 86 4 69596 9

(114) 8 9695969 8 6

(115) 8. 577 89 476 6

(116) 69 695 846969 79 6789 58 6. !"#$%#$ 6 658 7 97 4 57

(117) 9 8 &8 6

(118) 7945"'()%'(* 89&898 6764+,'(-%$./0 ,'(-%$.01297 6764+3/8 7 78 9 6897+4/5

(119) 89

(120)

(121) 562 6 794. 8 78878 786688 8957896 :89549 ;94

(122) 96< 348 4 = 6

(123) 7 97 4> 7 78 9 ?@ABC?DC6 9 6. -62

(124) 69

(125) 84 66

(126) 69

(127) 96 627 689 58 9. %$ 6&7 76 8 678> 7 78 9 EFGH?IJC45 76 576K 4 79 679 6 9

(128) 69

(129) 78 579 5 8> 7 78 9 LH?BCM "N9 78 2

(130) 78 778 6579 6766 6

(131) 6669

(132) &89 45 9. 64 9

(133) 8 9695969 8> 7 78 9OPQRSTUV6 5789 78.

(134) &89 6299 W 574 68> X2)-YZZY[%$#\$"N]%N^N%-()%Y [_$8 9695969 88 6

(135) 89 5 7 78 9 àUbcUVd> e 6 6 9

(136) 78. !&8 8

(137) 68

(138) 8 8 67659 6768 68 678 76 8 8>. X

(139) &89 678

(140) 58 &8 f895 5 89 &8 65687. gO. hO. . 01.

(141) 345678

(142)

(143) !"#$%%!!"

(144) &'4878 4(

(145) )*+6, +6- "%.!"$.$%%.%/),6,(75 30,+ 8)37 )* 1#%% 6-

(146) 5)*0

(147) 51 8 )10

(148) 86+ 2 3 4 4 53 78 8 465( 46- 6

(149) 7 )3

(150) 8

(151)

(152) 848*437 .!$9:;< =>=>?@ABCDBCEFEGHIJGDHKLJBMHNOHKBMHPGGIKBQCGEEHRI I S

(153) ,3

(154) , 4 -306-

(155) 5)*0

(156) 56 0

(157) , ' 4 3

(158) )*48 &4 4T 54&

(159) 04*

(160) 0+' +6- 6,+

(161) &'4878 35 6, +6- 6

(162) 7 &+8 *01 U+)

(163) 3 3

(164) ,

(165) 6+6-

(166) 5)*0

(167) 51 64 3

(168) 8*(

(169) %!"$.$VWXW6

(170) ( 8+)*53

(171) 848 *437 8 30,&(1 6-

(172) 07& 03Y 6130,+6+Y

(173) 6,+

(174) 46 *406,+6+Y 6-

(175) 07&8*0

(176) &+ 51& 8 *0436 Z40643

(177) *043 30

(178) ()*4( 46Y )*0+ 46 4 4&

(179) 56, +6 6,+ (53

(180) 3

(181) 0*+3

(182) )*0

(183) 46 [)*

(184) * ')* 85! #$V!% .!-306-

(185) 5)*0

(186) 56 8*70 '9\];< ^40,5 %!$ %%.% .#!#$%%! 6

(187) ( &+8_%# #..%%`!"%.!"$.$%%.% . .abcdefghihjfklcmnopqfrhsntlfuonnslfvlwhxclo<y#$ V# .z%V3

(188) 6

(189) *

(190) 8+6Y )*57 1 6-

(191) 5)*0

(192) 51 {|{

(193) 04,

(194) &6

(195) 46

(196) &'4878 35 6, +6- }3533 77 * 465( 6,+ 0&3 0

(197) (783

(198) 8+~ ^4 3

(199) )*48 56,&+ 31 3*78 6

(200) 76+

(201) 30458 3048

(202) 3

(203)

(204) &T)*8

(205) .%# / ! . z$Vz. z9;< )3455 31 3*

(206) 8 abcdefghihjfklcmnopqf rhsntlfuonnslfvlwhxclo. %z$:< 0, 86,) 4 6-

(207) 0

(208) &4 8T6

(209) 84 } 07 6576,+ Y 07 3

(210) &*+~ :# :<0, 86,) 4 6-

(211) 0

(212) &4 46,+T 67,(

(213) 8+6- 51&

(214) &8

(215)

(216) 8+6- \# \<. %(

(217) )*

(218) 3 4 , 30, 86,) 6-

(219) 0

(220) & 8T6

(221) 8 51& 46,+

(222) 8 \# :<. %`%!"$.$WXW +7' \]`$:# <. %(

(223) )*

(224) 3 4 , 353346 77 *+6 51& 0&36 0

(225) (783

(226) 8+6:# |,6 6

(227) ,7 3

(228) 7' ¡ 07 , 6-

(229) 5)*0

(230) 56 {|{ 3

(231) 8+7' 6( 5 :# . 01.

(232) 3454678

(233) 85 78 !"# # # # # # # # ###$#%&'# ()*+,-!.-./## # # ##### # # # # ###0#%&'# 3454674 142 4 3468 56#789:;<';=9:#>?>### # @A6B#CC9:D:#########EFGB#CHDI:J# # A#%&'# G6#789:;<';=9:#>?>## # $6BKA60#CC9:D:####EGBLKFG0#CHDI:J## B#%&'# F6#789:;<';=9:#>?>## # B6LK$60#CC9:D:####E5MLKG0M#CHDI:J## F#%&'# 06#789:;<';=9:#>?>## # 06LK06M#CC9:D:####E5BBK5AM#CHDI:J## 5#%&'# 3454678 N8683O

(234) 68 PQRSR!".-T-.TURV"/WURW,W-VX,-VY,-TU""*# # A#%&'# # Z

(235)

(236) 64678 [7 8 O[18\8 18 77 5

(237) 76684 # ];^_;## # # # # # # # # @#A#%&'# # à<9b;#%=cÎ9%9I9d_;# # # # # # # $KA#%&'# # ]=cÎ9%9I9d_;# # #######################################################################FKB#%&'# # ecd;:c#G6#fC9Iagh&9^c_;#&=a';=hc#=9i%9i_c^c_hc#8h%;=b89:;<';=9:;Chh#=9Iih__;j# ^H#klmnopqrsrtpuvmwxyz6# # {-TU""S,R/,-U-U"R"W,W-VX,-VY,-TU""S-.""-X ,-U.R/|QRT!-RS"RUX"YW-VX,-VQR-.!-.X}=9^hba# -./S~Y!TVb89:;<';=9:}#>?>#@5ML#CHDI:#,U/.XX"S*/Y ,R.T-./YVQ+"U"RU"-T./XU-"/Y-U-Y,S!V,/T../.RTU =9Iih__aC#^#&h;=}_&}#%=i;I^bi;<"SW-,-+/.-.S#556# X/"RSUS =9i%9i_c_h;#<'c^hc_;#j;<'#iâ&:;#"-T-,-.Y-Y"-X,!-UX-Q .-.!-VQ+QTR,Q"T-,.""!-YU!QT"/RSR"R-TXR.-+,RUQ V"U"!-SXUX-,QT"R"."RU.RXUURQ+U-+SR.-./WTU-X+ Y-T/W -"RT- U"R" X* R ,U/RT W,-U/!-/U"S -XR W,W-VX,-VY,-TU""SQTUU,R.T-./Y-U-YRY W-VX,-VQ R-.!-.XQ,-./,.#?:c';H9#jT/"*."*Y-T*,-U-U"R"R 8h%;=b89:;<',-VY,-TU""SX*+RTR"RY-VQVR,"#-.,TURS*-+"-| C}'cbjh#H;_}#qkqpsx#:}d#RS*X-""R.QU"R"/YXR"TR,TY ,-U-U"R"RS W-,-+/-.-TQTQS,"-,-T"-YQRS!"Q#qkq# . 01.

(238) 356789

(239) 56975569 9 9 59 9

(240) !"#$3"%&'3()*+,-".)-"%3)3$'.'#(#)#,-".)#/698 6069 97997 9 5 9591 23&3)'#(#)#,-".)#34.#34*!3&.*)#.*+,3/#.!-5$#)363,#4'3$#(#)#,-".)-6 !-'.*$*!3)-6.7 554!'33"/#),389&'3()*+,-"#6*$#5:$34)#/ %'3#4"%*$#+,#4*$#6'' 4*&.'))#/ !-5*4.-+,-!3)3 /#+, 6

(241) ;9 ,#"%)'53 +#5!#)"/*)*!3)'3*43.<=>?@ABCDEFCGHIJEKLDEMNOPGFGNPGNDIQRMSGITUFCEVEWLDEMNX8 Y 776695 Z[\Y ]6

(242) 6 9676^ 9 96

(243) @Q_ÒIQMCaUGRLbGIWcLENIRGLWDEMNX1d7

(244) 569 9 5659

(245) 6 975 69 )33*&+,3!'#+#5!#)"/'JeJO` 5 9]6

(246) 9fLDEMNLCI_GNDGRIVMRIgEMDGWcNMCMKaI hNVMRULDEMN@%,,3ijj!!!88)"k'8)'68%'%8(*lX8 23&3)'3 ,35'# 0 7

(247) 5 9 65*!'"'# :.3+3&)'*)#m 8 6 ]9^ 5

(248) 9

(249)

(250) 96

(251) 9

(252) 793'#4!+.#(*+,*3)'333"/#),3m :759 75 569m!-)*+'68nop89".#+)3'&#),-q'53"/3'$#".#)'#'+,*,)'# ]86;959 ;0

(253) ] 9 r)3".-)'*!-"%stuv8?.3,#6&'3()*+,-53 9766

(254) 66 ]0

(255) ]8 9 9 9 59 9

(256) . 659995

(257)

(258) 9 76757 899 0!-+*5'6 5

(259) 9

(260) 9 5 997 9797

(261) 9 9 59 9 4*&.'))#/8 wxwxyz{|}~~}} } | 666 69 688

(262) ] 9^ 9 ] .%'3#4"%*$#+,#4*$#6'4*&.'))67 69 &*&3,5*!*!'#$*63".-))'536' (#)#,-".)-6'm6#,6]

(263) ; 7 sttv8

(264) 7

(265) 6 ]6

(266) 9

(267) 666 69688559^ 698i d97¡ 8

(268) ¢£¤¥657 ]95£¦§65$:k3*6#)*33:.'# >3$#)'#,-,*)': ¨*&3,)'!-!'3&4*&.'))-!5'#4:)5:34

(269) 9

(270) 9 9 ]9^ 9 :54#!)-"%3'#4!+.#(*+,*3)'3©7 ]95ª«§65 8

(271)

(272) ª§§651 9-+*5'3*.'*6"%*$#+,#4*$:=¨=¬o6(j&$ . 01.

(273) 367897

(274) 7 8 3!"#$"%$"%&'('$"!)%*++,-. 3/9

(275) 01 32

(276) 7 7. 7304,567 . &&89:';"%&9<%!$9#!"&;=>%?&;=@"%$"9$=!A&!)=$$"BC;&D=)=B&8D)=?('9E&">&@9>$& 9BD%#F"G&HI6F%'$"%&D=)=B9&;=:'J8"%$"&!A9D9<=&;"%K!9;%?&L&$%M9&8!?%$'&

(277) N*O19 P QRSTUSVWXYWZV[\SVW]^_Û`W 6<%)&!)=$$"BC;&D=)=B Qabcdefcghigjckefcgblmlno 6-

(278) 033790

(279) 091 Qp^TÙSVWXYWZV[\SVW]^_Û`W6q&"&;"(!%?&!)=$$"BC;&D=)=BE8r9737

(280) 31 WWW@">>=!s-5tu Xvwx Wabydz{oecnge|}mlefo~lW W D)%9@9;%&)$!)%$"%& F&)D9)L@"3718'9M%$%)=&!A9DC<&:%D!9;96 $!)=$"9;=!A&@"9&9BD=!"%E&>%&#DC< 39O8 13 3 90330 78DBD=$$=@E&&?%M9&!)=$$9#G&9MD=;&$"%)<($J&D9F(&;&D%MLF!?"&$8"(!"&@"(#$"& MB"!A#!"$=&$!)=$"9;%?&s-*-t*8D9!%:C;&BD)%8$"(!"&s-7t9D)&8D9!%:C;&

(281) 1 13077 3 7

(282) 30E&&'B>%&;&A%)?"&@9$9!='C;&"&F%LB9!='C;u9@CDB"& :'$9;"J&<D"%D(&@"()=&BD;"J&&B9@CDB@"&@"(#$"&MB"!A&$!)=K& ;#$"%&)<LD)%$"&?%M9&L$B!?"&989;"?J&)&"$"!?!?(8D9!%:L&@">>=!9;%M9& $&89)"9@"%&B9@CD9 0 s-t7.

(283)

(284) 1?JD9);C?&<F:)B"&@">>=!9;%?&s-tu 8

(285) 9

(286) 37O 890739O7

(287) 1r

(288) 1"%F9!)=$$"B9;J&DC;$9;M(E& B'CDJ)8%;$"?J&B9@CDB"&#DC<9$B ¡¢£¤¥¦§¨©ª¢£« ¬DC<9$%B&'9&89?%=$!)&;D:';&8:B"!A&B9@CD%B&#!"#F%&8D)=F%M?J!=!A& 87r7

(289) 0 0)J!)=&9103 0*

(290) 1);=!)?&:<9&;"9!)$& 03 0r1737178 7

(291) 30u &:'D9$=&#;"'&$!)=$"&#DC<9$%B& . 01.

(292) 3456789 3

(293) 3 97 97 6 84 8 898

(294) 464 68 766 3

(295) 68 78

(296)

(297)

(298) 8!"#$%"&'()")*()+,#"-./ 0 -.$13947

(299) 7 7 438 4

(300) !70 727!7

(301)

(302) 87067 647 434 3 44 5*),"-6$*-/7/"-*.97 0 97

(303) 8738 9*"#$-.:67 97 98 70"7*1,"(768 6 867 2848 37 68 .*7 43 7 704;

(304) 388 < 60567 3=>":.7$?@ABCD?EFGH 78 6378

(305) 868

(306) 4 78

(307) 438 37I68 ;

(308) 7 5

(309) ;! 3; 7 )"(*%$77 97 797 78 J ! ;

(310) 3 5

(311) ;! 378

(312) *7,/%$7/KLMNDGHO@PE?GQBRSC?PO@CFT?@UVW:./77),)*7)"#/"-*.77 0 44=$7./X 38

(313) 64 78 40 4 7 8

(314) 64 !

(315) 4770& Y4 3 Z[\]

(316) Y

(317) 4983 7 7 ^6897 34 5797 862 7 3 97 7.

(318) 64974

(319) 8 ;

(320) 7 5

(321) ;!

(322) 60 70 8

(323) ! _ 7 78 `6 ?@ABCD?EFGH&abcde-")"7$- 78 8 8

(324) 484 f

(325) 62g. h 3 78 34 4!865i 3 5

(326) ;! 7$.7*7$%"1",$"-/:./77)* 37 68

(327) 89 60 7057;37 78 ;

(328) 4 3 97 5

(329) ;!34 64778

(330) 9j7 64 klmno=?@ABCD?EFOEPA?pFq?APp?EOrF@TPsORCBpVtbcu8 ^85i 9 ;j78 70 I8 ! 6 8 988 NvwxPP@FCpFRPBrFA?y&z($7$)*.", "#+,*$#5

(331) ;! {=

(332) 774 707 !86567 $7./X+/7,*./,($7)*.", N?xvw|xP?@ABD?EFOEP@FCpFRPBrFA?PUS@CDOU?} 3 !86567 762 )"`

(333) ;3 *),$,-*6/1-">",$-/7/t~eu&8 ! 6 !

(334) 78

(335) 3

(336) 8 8 ;

(337) 3 7 79 88 '*.,$71/571$1");

(338) 8 7057 762 64_ "#"18 43 68 649 4 4938 ;

(339)

(340) 3 7

(341) 8

(342) 87 64_ .*5

(343) 87638 gg649768 X"7"5"+5"-*7 %*7"./7/& "#"1$ "778 878 0I87 3 7 383

(344) ;

(345) 8 7057 762

(346) 2 8 645i !7 8

(347) 6973466&< 3

(348) 62 `7976462 74 567 7 ;34 *),/#*,"-$X?vw| 8 435i 38 70 7

(349) 843

(350) 37t~bu& J 84 8 I8 !4i 433 4 3 3787 78987878"-*.-.$. !

(351) 4770 840 7 647 3

(352) 5

(353) ;! 64738

(354) 8

(355) 70 34789 #,-*678

(356) 8 67 48t~~u&988 7

(357)

(358) 478 2 6

(359) 8 60 7 280 48

(360) 37 7 . 4

(361) 97`8

(362) 6478 ;

(363) 7 705 762

(364) 3 43 *7,/")+/1*:/7$W

(365) 76 6 987878 97

(366) 87 8 0 567 t~ u& . 01.

(367) 3456789

(368) 94 6

(369) ! 4

(370) " ! #$!%&'!(#%')!%!!*#$'!*#%+&!*(+!'$(!+##+,&(+!-./01! 2. 3 49 5 49 6 3 7 6 8 49"47

(371) 9354

(372) 39 486

(373) 8 :! ;$#<&!*((!456789

(374) 9+!(+&&!8 49"457=!>?@ABCDEFGHIJEKLMND GEOOLPEGDJLQEOQHKROLSLFTDURVIHOW)!49 6 7 6

(375) ! 7 6 69

(376) 9: 7 9 -.X01! 3456789

(377) 9 "

(378) 9 9696 (!*#+!<(#$+%+&)! !

(379) 6 " 6576 7 97=

(380) 7

(381) Y!&$#%&+)!%#;Z#&)! .

(382)

(383) 57= 8

(384) [ " 5

(385) 94 !-.\0!#(!*#%&#$+1!]94 6 45 <!4

(386) 68 5 49 6 2 49 6 9 22 -.^0_ `8 89a "9

(387) " [ 394= 45 4a 945&#'%## 6

(388) 5

(389) 9644a 49"9 4 45"7 #(!*(Z'$#<!645

(390) 54 : 9 8_ ! b 45

(391) 8 c79"94 8 456789

(392) 9644 9 69 = 49"9 <!543 5 6 45 94!*((!d;#<&!*#e!

(393) 9354

(394) [ 49 65 " 8 49 65

(395) 4 9_ ]#<#$'!%#!f&%#(+! 6 "5 78

(396) 8_ g49 6 944 8

(397) 9a 79"94 = -.h01! i 396 . 9a 456789

(398) 9" 4 97 4 5

(399) 9 49"9 49 *#<%<&!(*&!!#,&(&'!(*&+!%+#!$#!;!'(#$(&! 'Z!*(<&!EFGHIJEKLMN1!j<+!(*<&!%#!*(<,!

(400) 9 3 8 35! &%+#,'+&+d!&$!*9

(401) 945"7 3_ `8

(402) 945"7

(403) 57= %&!(#%'!!*#%&,&$+&!.!#(!*#$'#<&!4 456789

(404) 4937 222 !#e%#!kk!d*+&+)!(+&&!l!!Z!m!!n1!3456789

(405) 9 9644

(406) 69 =!49"9 494 )!*#65

(407) 57= " .

(408) 4965 -.o01!! ! ! pqrqrstuvwxyz{|}~ yz} ! 9

(409) 4 " 7

(410) 9 66c5

(411) 7 456789

(412) !9 7a 8

(413) 7= 456789

(414) 1!n%&!%! 6477=8 35 45

(415) 8 39 496a $#!#(<#'!89457 6 499f&(+&#<+d!-01!b9

(416) 69a .

(417) 5 4

(418) ! #<#f&(+&#<,#!496 8 69 66c5

(419) 7!456789

(420) _ 969 .

(421) %!

(422) 57=!;d&(;+!;#'&)!99657= !

(423) 64 679 8 39

(424) [ 9

(425) [ 39"

(426) 58 68 7[

(427) 7 " 5

(428) 95 493795[

(429) 9 6

(430) !''d#;&! *#'!(*&,#!-01!! . 01.

(431) 34546789

(432) 847

(433)

(434) 958

(435) 447

(436) 5

(437) 9 78

(438) 5748 498

(439) 674

(440)

(441) 47

(442) 6

(443) 7

(444) 4

(445) 8!"#$#%&#'(')#*+,!),'-)./(-%&#'01(121(-!*&'

(446) 47

(447) 3

(448) 74

(449) 547

(450) 3

(451) 7

(452)

(453) 9798

(454) 2/67,.-8/' 01!-2.9*!)1(*&'46

(455) 6

(456) 4 4784

(457) 7467

(458) 6:

(459)

(460) .-)'&-)'.9*!*)'-81.,'

(461) 5

(462) 63764;

(463)

(464) 8

(465) 8

(466) 4 9

(467)

(468) '9587

(469) 84<' 8784;

(470) #%"'379=

(471) >?@AB'C7579

(472)

(473) 498

(474) 5

(475) 674

(476) 684 478

(477) 7B'D1%"128#' 21'353498

(478) 9 778

(479) 475979E

(480) 4

(481) 34 7

(482) 7

(483) 4

(484) 4

(485) 4498

(486) 0+1.*-8B'F-7-'GHIJ' 94

(487) E 54 =

(488) 674

(489)

(490) 9 4;

(491) 58=' 21'(/.(-+8-!#-'+*-)./(!/%"'K1+7'.9*!,4

(492) L47

(493) 7

(494) 47

(495) 5

(496) 4

(497) =478

(498) GHIJ'8

(499)

(500) 46 8;

(501) 6

(502) 4 4784

(503) 7467

(504) 6:

(505) 45 9 4

(506)

(507) 4749E

(508) !#*21$1+,'MN-+O#!#!/'%8/'.*.+-"/2+1$#10.*+/!/'>@PAB'' Q7 9

(509) 5:

(510)

(511) 4494

(512) 674:

(513) 4

(514) 5478

(515) 9 =;

(516) 486

(517) 6/6.*7,'7

(518) 478 :

(519)

(520) 9 784;

(521) 58=

(522) 6

(523)

(524) 8469

(525)

(526) 4798

(527) 12'+128-&,'#'9E44

(528) 6R9

(529) 4479E4

(530) S

(531) 47 8

(532) 8469

(533) -)#7#' 9 7784 8

(534) 447 8

(535)

(536) ;'E89E5 84:

(537) 746987878

(538) =789 :

(539) %,)+ 94:

(540) 4

(541) 4

(542) 877

(543) 547:

(544)

(545)

(546) 4;

(547)

(548) 4 784

(549) *7#-!/' .9*!),'-81.,<''0+12,)%&*'+*-)./(!/%"'K1+7'.9*!,''8

(550) 5 878

(551) 55

(552) 56497

(553) TU/%#!-'?V'>??AB'W#*8-978

(554) 6

(555) 9E6 784

(556) +*-)./(!/%"'K1+7'.9*!,'#'.9*!),'-81.,' 01(6.-&*'=67

(557) :

(558)

(559) 6

(560) 645

(561) 449=

(562) 674

(563) 8

(564) 547

(565) 8-0-9!*O1B' '. . 01.

(566) nopqrstrutruv wxwtrqyu. }~ rx nruptsv }. z{|}~. Z[\]^_àbcd efghhijklmd. } . {. {~ }{~ } . . . 456789

(567) 65 96 5867 89 896587

(568) !"#!$%&'(95 5867 89)*98 658877. +','$#-",'. /96 70 899/87 89 658877 559 61,2-"#,&34'+3 )/ (9(687 75 66885 5() 65887 6799*8566. 898566 8

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

(570) 23567889 9

(571) 33

(572) 3!33"#$ %& 9'(& )33*+,-567.'56'89'/%&%78&09*12$13-45 326

(573) ! 5

(574) 63

(575) 5 3

(576) 7'89%898:75;< =

(577) !

(578)

(579) 3522

(580)

(581)

(582) >

(583)

(584) 93

(585) 5 3 6?!

(586)

(587)

(588)

(589) !> 3@A

(590)

(591) 3>! 357 33?B'88%7CD35

(592) 637

(593)

(594) 5 5>7?@E

(595) 7

(596) 3637) C98.9B'9&5(4

(597) !

(598) !353 3!

(599) 5 8:'($ >3

(600) !

(601) 535 3!3(6522

(602) 3< F&

(603) !6 !3! $> 3>37

(604) G'65 3

(605) 37

(606) !@A

(607) 3

(608) H353! 3!> 3>233 !4736

(609) )5 3 IJK

(610) 3 ? 3

(611) !>!*1L-< MNOPQQRSTSUVWXYZUTQ[T\]^YQ]_TUYQàbcdefghijklmnbcogfgpoioqrsijtgUW_XYUS]VY_uQ v9':'85(&/'958:8w8&567898:&('/%8C&9%&C96'x':/67/% 908&8/6&58:&89D 98x7:9xD&.8'y8 ! 3?

(612) 3

(613)

(614) w8&567898:75;<z8C&959D 8 2?{3 35

(615) 6

(616) 7?4!?G&x&89'|}~~ 3!

(617)

(618) ! 3 !3 3)434

(619)

(620)

(621) 5 5;8.'/%'98.D$C&.'89'%7%889D$5D 9675&533!>!3*1+-<F9':/67/% 9' 5!5 !

(622) ) 333 ! 88'x8 3385'879767 &<!!35

(623) 2)!5423 63636

(624) 9767 &89'C8('x7856'23463 33!5:6&('08'98%'9& 5(' 5>5

(625)

(626) 35

(627)

(628)

(629) 5

(630)

(631) 235 y'8'%756870@ 353

(632) 332

(633) ? 53! $ >! 54

(634) !

(635)

(636) 3)>35

(637) 2

(638) ! 3 3 &567?3!3958:8w8&567898:75;<F9'6:7 .'C80858' 5

(639) 7

(640) )>!

(641) 38G9&68:'0'%8x785'876&&:&8/8:&89&C985'/D 522

(642) 37

(643) 5

(644) 263 35522

(645) ?('/656':8 9'/9' G'68G(&:8:70*11-89&6835'

(646) 3

(647) 3522

(648) 37

(649) 8& 275;('y8/%8C89&5;986:8(D< = 3

(650) 5

(651) 3336

(652) 53 !

(653) 733?

(654) 3

(655)

(656) w

(657) ?5

(658)

(659) 3423

(660) 33!

(661) 7353

(662) 5 . 00.

(663) 35676879. 9

(664) 6 9. 796 7 76 656 68

(665) 6 9! 89! 76 57"! 875 6# $ 6 67 6 % 8 566 6 6 57" 6&&9 6 5 8 !789 # '(5" 7 7! 86 5 6 7! "! 3)(*+, 69 % 8 -./012-3456789:;<66 68 5. 9 5

(666) =3(3=>?@AB=(CD676 6 # E9 8 "!5. 9 68&76 9 6 8 -./012-3456 6 "7 676 7 57" 6&&9C+,65!5769 "8 5 8 6 D+F*?G3( 79# H &6 6 "5 9 "5 6 5 *AGI9 66J

(667) 69 "6768796 68"6 % 8 7! 86CK+=3(G@=(B(F*@>AKL( >AK+=?=3(D?=(LM66J# E" 67 6 % 8 7! 86 & 6 79 6 5 9 6966 9 76 . 86 3(,+KN>3(=3()OPQRSTU30VT6-/4W1-/T /43W1W140.X78YC8ZC8[:# \"59 57" 6&&99 576 6. "7876 9 % 8 6 9 6 9 69 6

(668) 6 57 8" 6 "9 . 69 # ] 6 9 & 6 " 9 87" "66DN@AD+)+GA 5676 7! 69 56 69J AGIO^_`STa53b-TVWc-Tc-30d41eC ^_fSTa53b-TVWc-TW.W3eb4bX78gC9hC9iC9j:# k 5!l " 6 9 "7876 & 9 6 66 8 68 8 766 6B?KmN(@+=?=F)?n=(*AG@=A OQopST6Wq.-14dTr-b0.W.d-T46Wq4.qX79s:C*+)+nN?t3?K+)DM*(N+>?OuvSTd06a51-rT 1060qrWa2eX+N?@T5 67 7 8 58" 6 7 6w 6 786 9 OpQvST4.146WT6-/4WT124dx.-bbX7YhCYi:;y=?G@(=3(*AGI)(*+,,L?+G(=ANA@AK? F(NG+>+w 69 "6 & 57 6 66 6 3+zF(N>?GAB=A)3 3KL3=3G@=A)379YC9ZC9[:# <66 6 {|} 76 $~ " 76 9879"96 NA@AK?F(NG+>+w 69

(669) 6 6 "5 C>AF+K3(K+F@*? 3576. LMzB?K>DN@AD?,KM 68& 6 676& =?DN+)3(=3+>?=3(N(=*n(=+>FK3(;@(N@(B9879"96 & "6 " ML*N?F+=+nN?t3?=?G@A=3+>?

(670) 6 F*+FM=K+>+ 7 5676

(671) 8!768 6""6 577 8! 76" 76% 9 & " 566 6 9"86 86 9 76! 66 +N?@"7879 66 9 69J 87 979g:; . 01.

(672) 34543789

(673) 888 !88" #!""$ % &'()*+,-./01234156768491:;26<=6>4?<@2:091A:402BCB:491?862:02:4?<6D/>4?:4?2 6=4E0F25GH2>2IJKK2/6DG2L9M/?B1?:N0A?/O210P2=4?/>E1A2=6N40/2QRS2>AD6:0:A216EB0F2 *.TUVU.)WXY.Z),(,.[\]()+W\^.'._^)X^.àbcd2eEB6BC2=6N40/G2EB0:6>4269?:021N40:A2 P/?<:49A2BCB:49A2/0N4?::?52=6<2>=F-*(f.f(]'^B6/g>O28Fg>:4?2B7?:DG2016BGh. G>07:40:A9M2=6210B/1AN0:4G242=/1A>/g9?:4G2=/1?=FA>G2X)*'.*.\î,-\'Y.`Tjck. S6DF0<:A2N?9M0:41N2:4?25?EB.\^]^l.>2=?F:42=61:0:Ad2m>0H02E4C25?<:0DO24H2:^.+XYn(X. 1>4CDE16:?862 =/1?=FA>G2 D/>42 =62 GEB;=4?:4G2 :4?<6D/*'(\'^h. ]WioW],'. ]W.MA=?/=670/A109542D6Ng/?D2P/g<pF6:D0O21>4CDE1?:402:0=FA>G2>0=:40.àTh.aqh.arc. ]W.49M2>:CB/102420DBA>09542P/g<pF6:D6>?52stuvw`Tjh.axcd2SFG86B/>0F?210P.10ND:4C94?2 =/1?=FA>G2=/1?12:091A:4?2=6>6<G5?21N40:A2?DE=/?E5428?:g>2=/1?1.36E36/A7095C28?:G2 stuv.'.*.XW\+(X*(\i5421>4CDE1?:4?20DBA>:6P942B?86H.(\,-fY.àjh.aack.yz-.]*^.n(. Z)Wi(+-.Z)W*^<1;2<621>4CDE1?:402EA:B?1A2{|24.*.XW\+(X*(\i}'.]W.)W,+,(),(\'^. \î,-\'^k.~Z)W+,i,W\-.+io(f^n.^Xn-*î}'.stuv.'.<140F0:402B7?:DG2016BG2=/1?<EB0>402 -i'\^.xk. .. . -i'\^.xk.~Z)W+,i,W\-.+io(f^n.^Xn-*î}'.stuv.42<140F0:402B7?:DG2016BGd. . 01. ..

(674) 3456789 8

(675) 8

(676) 695 8 8 9

(677)

(678) 9 45598 498 8

(679) ! "59

(680) 5 95

(681) 8 8

(682) 4 84

(683) 5#8

(684) $%&%8'

(685)

(686) 8 (9 8)5 5* 95 +,-./012%.3,+45%362+5478$%9:%$%/;<$08./0<$,%. 957 56

(687) = 95 &,/2+>-,?,78$@%% A,+,<$0%BCD%80.?%<$0$<&,/>8<0%$%E0/3$07/<0%+-,%3,780<?,@%F012% 36/0362&,9 8

(688) 8 8 555 GH

(689) ! F0+<,4%<78 4

(690) I 5 5)

(691) 8

(692) '% ?012%?0.?5! 8)5

(693) 4% 88) 48J '

(694) 5

(695) 8 8 ?2%956

(696) 9 8

(697) 8 9#8)5

(698) 44 8 5 48 J

(699) 88 58

(700)

(701) 8 5=

(702) 8 ) 8 K

(703) J 4 89

(704) LJ

(705) 575/8$M%7/,.% 2+%+0N-,78$%+2%32;$,65%26,/%;859 45

(706) 689

(707) ?<$7>%OPQM%PRM%PST@%% " 89 9

(708) 8 48 45

(709)

(710) 8 45 5I 5 4 8 %RUVW%12+/$<@% "5

(711)

(712) 8 I 9

(713) ' 45

(714) 8 8

(715) 5 8 848 8! X

(716) 8 78

(717) 5 8 #8

(718)