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Underexpanded stent in left anterior descending coronary artery treated with intravascular lithotripsy

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216 Creative Commons licenses: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY -NC -SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Corresponding author:

Bartosz Górny MD, 2nd Department of Cardiology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 75 Ujejskiego St, 85-168 Bydgoszcz, Poland, e-mail: gornyb@wp.pl

Received: 17.12.2019, accepted: 11.03.2020.

Underexpanded stent in left anterior descending coronary artery treated with intravascular lithotripsy

Bartosz Górny, Wojciech Balak, Gabriel Bielawski, Michał Ziołkowski, Marcin Walukiewicz, Grzegorz Grześk

2nd Department of Cardiology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland

Adv Interv Cardiol 2020; 16, 2 (60): 216–218 DOI: https://doi.org/10.5114/aic.2020.96068

Calcified plaques are associated with procedural chal- lenges and suboptimal outcomes of percutaneous coro- nay intervention (PCI), which can result in impairment of stent apposition and stent underexpansion. Good re- sults were observed after laser atherectomy, rotational atherectomy or high-pressure balloon dilation [1]. Intra- vascular lithotripsy (IVL) is a novel alternative in plaque modification. It is effective, safe and easy to perform in severely calcified segments [2]. The coronary IVL catheter is a single-use device that contains lithotripsy emitters enclosed in an integrated balloon. The emitters gener- ate sonic pressure waves creating a field effect to treat vascular calcification. The IVL catheter is available in 2.5 to 4.0 mm diameters with 12 mm in length and delivers 10 pulses/10 s with a maximum of 80 pulses on one bal- loon catheter [3].

We present images from angiography and optical coherence tomography of a 58-year-old man who was admitted to the hospital in a tertiary center with ante- rior-wall ST-segment elevation myocardial infarction. He complained of chest pain from 30 min, but felt angina symptoms in the last days after walking 100–150 m. The coronary angiogram revealed severely calcified critical stenosis of the proximal and middle left anterior de- scending artery (LAD). Several inflations with non-com- pliant (NC) balloons (2.5–3.0 mm) were done and two 2.75 mm drug-eluting stents (DES) were implanted in the

LAD. Unfortunately the proximal stent was unexpanded.

A decision was made to transfer the patient to our clin- ic to perform IVL with a Shockwave device (Shockwave Medical, Fremont, California, United States).

We performed angiography and OCT to evaluate stent expansion and assess the size of the plaque cal- cification (Figures 1 A, B). Next we decided to use the IVL Shockwave C2 catheter (3.0 × 12 mm). Four ses- sions with ten applications were performed. After the first pulses the balloon remained partially unexpanded in the proximal stent, but further cycles were done and the NC balloon (3.25 × 12 mm) allowed us to achieve full dilation of the implanted stent (Figure 1 C). Optical coherence tomography (OCT) showed complete stent ap- position with dissection in the ostial LAD (Supplementary Figure S1). It was treated with one DES (3.5 × 15  mm) and post-dilatation with an NC balloon (3.5 × 12 mm) af- ter stent deployment was done. Control angiography and OCT confirmed a good PCI outcome with optimal stent expansion and apposition (Figure 1 D). The patient was discharged 2 days later without complications. A mean lumen diameter of proximal edge of stent was 1,66 mm and a minimal lumen area of 2,21 mm2. After interven- tion with intravascular lithotripsy OCT confirmed optimal stent expansion and apposition, with a minimal lumen area 9,3 mm2 (Supplementary Figure S2).

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Bartosz Górny et al. Intravascular lithotripsy in underexpanded stent

217

Advances in Interventional Cardiology 2020; 16, 2 (60)

Figure 1. A – Left anterior descending coronary artery with underexpanded stent – CLEARstent view. B – Optical coherence tomography before intravascular lithotripsy. C – angiography after intravascular lithotripsy pulses in LAD – CLEARstent visualization. D – Final OCT – perfect stent expansion and apposition without dissection;

yellow asterisk indicates calcified plaque

A C

B

D

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Bartosz Górny et al. Intravascular lithotripsy in underexpanded stent

218 Advances in Interventional Cardiology 2020; 16, 2 (60)

References

1. Lee T, Shlofmitz RA, Song L, et al. The effectiveness of excimer laser angioplasty to treat coronary in-stent restenosis with peri- stent calcium as assessed by optical coherence tomography. Eu- roIntervention 2019; 15: e279-88.

2. Brinton TJ, Ali ZA, Hill JM, et al. Feasibility of shockwave coronary intravascular lithotripsy for the treatment of calcified coronary stenoses. Circulation 2019; 139: 834-6.

3. Ali ZA, Nef H, Escaned J, et al. Safety and effectiveness of coro- nary intravascular lithotripsy for treatment of severely calcified coronary stenoses. The Disrupt CAD II Study. Circ Cardiovasc In- terv 2019; 12: e008434.

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