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Heavily calcified coronary lesion treated by shockwave intravascular lithotripsy

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KARDIOLOGIA POLSKA 2019; 77 (9) 890

atherectomy (Boston Scientific, Boston, Mas‑

sachusetts, United States) was considered,2 but given the proximal LAD diameter exceeding 4 mm, we decided to use an intravascular lith‑

otripsy catheter (Shockwave Medical, Inc., Fre‑

mont, California, United States).

The left main coronary artery was intubated with an EBU 3.75 6F guiding catheter (Medtron‑

ic, Minneapolis, Minnesota, United States), and Cruiser ES ‑HF (Biotronic, Berlin, Germany) and BMU II (Abbott, Chicago, Illinois, United States) guidewires were introduced to the distal LAD and the second diagonal branch, respectively.

An initial predilation with a noncompliant So‑

larice balloon catheter (Medtronic; 2.0 × 15 mm;

up to 8 atm) was performed, and then a litho‑

tripsy balloon catheter (Shockwave Medical, Inc.;

4.0 × 12 mm) was introduced. Ten high ‑energy applications were performed to achieve proper plaque modification (FIGURE 1B and 1C). Each time, the catheter was inflated to 4 to 6 atm in order to facilitate energy transfer. The Shockwave de‑

vice generates sonic pressure waves that selec‑

tively crack calcium deposits without any dam‑

age to vascular soft tissue.

Follow ‑up IVUS revealed calcium crack and no intimal dissection. A noncompliant Solarice balloon catheter was used to predilate the lesion (3.5 × 15 mm, 25 atm) and 1 drug ‑eluting stent (Orsiro, 4.0 × 40 mm; Biotronic) was implanted.

Postdilation with noncompliant balloons was performed to ensure proper stent apposition (FIGURE 1D). The final IVUS confirmed optimal stent placement and apposition, with a minimal lumen area of 9.9 mm2. The patient was free from any symptoms and was discharged home 2 days af‑

ter the procedure on standard pharmacothera‑

py recommended by the ESC.

We present a case of a 72‑year ‑old man admit‑

ted to our center for percutaneous coronary in‑

tervention (PCI) of a highly calcified left ante‑

rior descending artery (LAD). The patient had grade 3 hypertension (according to the Europe‑

an Society of Cardiology [ESC]) and moderate aortic valve regurgitation without hemodynam‑

ic significance. He was a current smoker. Due to stable angina (Canadian Cardiovascular Soci‑

ety class II), he underwent coronary angiogra‑

phy in a remote center, followed by a physiolog‑

ical assessment of a borderline lesion in the me‑

dial LAD. The fractional flow reserve was 0.63 (ACIST Medical Systems, Eden Prairie, Minne‑

sota, United States), and the PCI was postponed owing to the complexity of a highly calcified le‑

sion and a need for plaque modification.1 On admission, the patient was stable with no symptoms of decompensated heart failure or unstable angina. Electrocardiography re‑

vealed normal heart axis, sinus bradycardia (50 bpm), as well as negative T waves in leads I, aVL, and V5–V6. Transthoracic echocardiography showed preserved left ventricular ejection frac‑

tion, without any significant wall motion abnor‑

malities and a moderate aortic valve regurgita‑

tion without signs of aortic root or ascending aorta dilation. The SYNTAX score was 11. Labo‑

ratory tests showed no significant abnormalities.

Coronary angiography via the right radial access, followed by intravascular ultrasound (IVUS, Philips Volcano, San Diego, California, United States), demonstrated heavily calcified lesions in the proximal and medial segments of the LAD (FIGURE 1A), with almost circumferen‑

tial calcium deposits with a minimal lumen di‑

ameter of 1.5 mm and a minimal lumen area of 2.4 mm2. Plaque modification with rotational

Correspondence to:

Brunon Tomasiewicz, MD, Department of Heart Diseases, Wroclaw Medical University, ul. Borowska 213, 50-556 Wrocław, Poland, phone: +48 71 733 42 57, email: b.a.tomasiewicz@gmail.com Received: May 28, 2019.

Revision accepted: July 29, 2019.

Published online: July 31, 2019.

Kardiol Pol. 2019; 77 (9): 890-891 doi:10.33963/KP.14917 Copyright by the Author(s), 2019

C L I N I C A L V I G N E T T E

Heavily calcified coronary lesion treated by shockwave intravascular lithotripsy

Brunon Tomasiewicz1,2, Michał Kosowski1,2, Wojciech Zimoch1, Artur Telichowski2, Piotr Kübler1, Krzysztof Reczuch1 1 Department of Heart Diseases, Wroclaw Medical University, Wrocław, Poland

2 Department of Cardiology, 4th Military Hospital, Wrocław, Poland

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C L I N I C A L V I G N E T T E Coronary lesion treated by shockwave intravascular lithotripsy 891 This case shows that complex, heavily calci‑

fied coronary lesions always require a thought‑

ful approach, and often more than 1 plaque mod‑

ification technique should be considered. Intra‑

vascular lithotripsy using the Shockwave device proved efficient and safe.

ARTICLE INFORMATION

CONFLICT OF INTEREST None declared.

OPEN ACCESS This is an Open Access article distributed under the terms of the Creative Commons Attribution -NonCommercial -NoDerivatives 4.0 In- ternational License (CC BY -NC -ND 4.0), allowing third parties to download ar- ticles and share them with others, provided the original work is properly cited, not changed in any way, distributed under the same license, and used for non- commercial purposes only. For commercial use, please contact the journal office at kardiologiapolska@ptkardio.pl.

HOW TO CITE Tomasiewicz B, Kosowski M, Zimoch W, et al. Heavily calcified coronary lesion treated by shockwave intravascular lithotripsy. Kardiol Pol. 2019;

77: 890-891. doi:10.33963/KP.14917

REFERENCES

1  Neumann FJ, Sousa -Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2018; 40: 87-165.

2  Dobrzycki S, Reczuch K, Legutko J, et al. Rotational atherectomy in everyday clinical practice. Association of Cardiovascular Interventions of the Polish Society of Cardiology: expert opinion. Kardiol Pol. 2018; 76: 1576-1584.

A B

C D

FIGURE 1 A – a heavily calcified coronary lesion in the proximal left anterior descending artery (arrow);

B – first application of shockwave lithotripsy (arrow); C – last application of shockwave lithotripsy (arrow); D – final angiographic outcome (arrow)

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