Europe North America Region rs Gene OR P OR 2p23.3 rs46659862:27755168 A G 0.96 0.84 9.07E-04 0.81 2p23.3 rs46653812:27757150 C A 0.96 0.84 8.08E-04 0.81 2p23.3 rs19726692:27767107 G T 0.96 0.84 8.36E-04 0.80 2p23.3 rs44932102:27768072 T G 0.96 0.84 9.46E-04 0.80 2p23.3 rs10800602:27768808 A T 0.96 0.84 9.41E-04 0.80 2p23.3 rs67490522:27772879 T A 0.97 0.84 9.45E-04 0.80 2p23.3 rs23846262:27773648 G A 0.97 0.85 1.69E-03 0.82 2p23.3 rs23846282:27774702 G T 0.96 0.84 1.05E-03 0.81 2p23.3 rs18202972:27774924 G A 0.97 0.84 6.39E-04 0.80 2p23.3 rs67509432:27777904 G T 0.97 0.84 5.65E-04 0.80 2p23.3 rs67610952:27778010 T G 0.97 0.84 1.20E-03 0.82 2p23.3 rs67066102:27778091 A G 0.97 0.84 6.43E-04 0.80 2p23.3 rs65477092:27783418 A G 0.98 0.84 6.71E-04 0.80 2p23.3 rs12714202:27787540 C T 0.98 0.85 1.26E-03 0.81 2p23.3 rs42601972:27794150 G C 0.99 0.84 1.09E-03 0.82 2p23.3 rs10205362:27794233 T C 0.99 0.84 5.04E-04 0.81 2p23.3 rs10165092:27796526 T C 0.99 0.84 5.69E-04 0.81 2p23.3 rs19191252:2780140C2orf16 G C 1.00 0.84 5.20E-04 0.81 2p23.3 rs19191262:2780141C2orf16 C A Geno 1.19 5.83E-04 1.24 2p23.3 rs13026622:2780762ZNF512 A G 1.00 0.84 6.17E-04 0.81 2p23.3 rs46659952:2781382ZNF512 G T 0.99 0.84 6.10E-04 0.81 2p23.3 rs46659962:2781434ZNF512 C T 0.99 0.84 6.55E-04 0.81 2p23.3 rs67380892:2781527ZNF512 G A 0.99 0.84 1.07E-03 0.81 2p23.3 rs46659972:2781698ZNF512 C T 0.99 0.84 5.96E-04 0.81 2p23.3 rs76047982:2782494ZNF512 C T 0.99 0.84 6.57E-04 0.81 2p23.3 rs62138962:2782829ZNF512 A G 0.99 0.84 1.07E-03 0.81 2p23.3 rs65477342:2783099ZNF512 T G 0.99 0.84 5.78E-04 0.80 2p23.3 rs67181282:2783375ZNF512 T C 0.98 0.83 4.79E-04 0.82 2p23.3 rs46659992:2783444ZNF512 C T 0.99 0.84 7.09E-04 0.80 2p23.3 rs1112707 2:2783805ZNF512 A C 0.98 0.84 7.16E-04 0.80 2p23.3 rs67379212:2783910ZNF512 C T 0.98 0.84 7.19E-04 0.80 2p23.3 rs67562382:2784130ZNF512 A G 0.98 0.84 7.21E-04 0.80 2p23.3 rs15284042:27846603 C T 0.98 0.84 6.47E-04 0.81 2p23.3 rs15284032:27846645 G C 0.98 0.85 1.32E-03 0.81 2p23.3 rs23846542:27847364 T C 0.98 0.84 7.77E-04 0.81 2p23.3 rs46660052:2785523GPN1 G A 0.98 0.84 1.04E-03 0.81 2p23.3 rs23846592:2785679GPN1 A G 0.98 0.84 7.74E-04 0.80 2p23.3 rs46660092:2785799GPN1 A T 0.98 0.84 5.64E-04 0.80 2p23.3 rs56001552:2785992GPN1 T C 0.97 1.19 9.25E-04 1.25 5p15.33 rs77261595:1282319TERT A C 0.99 1.19 1.09E-03 1.20 5p15.33 rs44495835:1284135TERT T C 0.99 1.19 8.86E-04 1.19 5p15.33 rs1113372 5:1306765 G C 1.00 0.87 7.26E-03 0.77 5p15.33 rs60622805:1309904MIR4457 A G 1.00 0.87 6.65E-03 0.77 Supplementary Table 8 Oral cancer results (5x10-7< P >5x10-8 )
Chr:posa Effect allele Other allele Info (Rsq.)b
5p15.33 rs65547585:1310152MIR4457 A G 1.00 0.87 6.93E-03 0.77 5p15.33 rs421629 5:1320136CLPTM1LA G Geno 1.17 1.90E-03 1.23 5p15.33 rs380286 5:1320247CLPTM1LA G Geno 1.17 2.04E-03 1.22 5p15.33 rs401681 5:1322087CLPTM1LA G Geno 1.19 6.03E-04 1.24 5p15.33 rs13178865:1323212CLPTM1LA G Geno 1.17 2.98E-03 1.25 5p15.33 rs466502 5:1325767CLPTM1LG A Geno 1.19 6.33E-04 1.23 5p15.33 rs465498 5:1325803CLPTM1LG A Geno 1.19 5.83E-04 1.25 5p15.33 rs452384 5:1330840CLPTM1LG A Geno 1.19 7.28E-04 1.24 5p15.33 rs370348 5:1331219CLPTM1LG A 1.00 1.18 8.94E-04 1.24 9p21.3 rs944800 9:2205089CDKN2B-A G Geno 1.14 1.91E-02 1.24 9p21.3 rs23832059:2206093CDKN2B-A G Geno 1.17 4.14E-03 1.17 9p21.3 rs15373789:2206161CDKN2B-A G Geno 1.17 3.24E-03 1.18 9p21.3 rs81810509:2206439CDKN2B-G A Geno 1.17 2.43E-03 1.18 9p21.3 rs35307549:2207175CDKN2B-G A Geno 1.17 3.45E-03 1.17 9q34.12 rs37655669:1339427LAMC3 G A 0.95 1.31 6.77E-04 1.33 9q34.12 rs78754789:1339471LAMC3 T A 0.94 1.31 9.14E-04 1.35 9q34.12 rs78582049:1339473LAMC3 A G 0.94 1.31 9.41E-04 1.35 9q34.12 rs10901349:1339564LAMC3 A G 0.95 1.30 6.42E-04 1.35 9q34.12 rs72768539:1339595LAMC3 G C 0.95 1.28 1.42E-03 1.34 9q34.12 rs72768539:1339597LAMC3 C G 0.95 1.28 1.39E-03 1.34 9q34.12 rs77452479:1339625LAMC3 G T 0.88 1.31 1.92E-04 1.30 9q34.12 rs1179103 9:1339710LOC1053G T 0.93 1.30 8.98E-04 1.33 10q26.13 rs201982210:126157LHPP D I Geno 1.99 5.43E-06 1.64 15q21.2 rs129102815:497859LOC10537G A 0.99 1.29 9.21E-07 1.13 15q21.2 rs108514715:498290LOC10537G A Geno 1.29 9.11E-07 1.14 15q26.2 rs125949015:968562NR2F2-A G T 0.83 1.22 2.41E-04 1.21 15q26.2 rs289505415:968594NR2F2-A T C 0.83 1.22 2.88E-04 1.22 15q26.2 rs239818015:968631NR2F2-A T C 0.84 1.23 1.71E-04 1.23 6p21.33 rs31306146:3147645MICB A T 0.99 1.80 1.20E-06 1.22 6p21.33 rs31306126:31482097 C A Geno 1.70 2.02E-06 1.21 6p21.33 rs18006286:31546850 A G 0.99 1.79 1.73E-06 1.25 6p21.33 rs31324516:3158202AIF1 C G 0.99 1.23 6.75E-03 1.26 6p21.32 rs92713786:32587300 G A 1.00 1.28 4.96E-06 1.20 6p21.32 rs17612856:3262057HLA-DQAA G 0.95 1.34 3.93E-05 1.15 6p21.32 rs47135706:32626040 T C 1.00 1.32 4.02E-04 1.28 6p21.32 rs92733946:3262708HLA-DQBA G Geno 0.76 3.74E-05 0.87 6p21.32 rs10492136:3262777HLA-DQBG A 0.97 1.39 6.97E-06 1.17 6p21.32 rs38288056:3263612HLA-DQBC T 0.88 1.36 8.80E-06 1.23 6p21.32 rs31297806:32647701 A T 0.80 1.33 1.21E-05 1.17 6p21.32 rs21570516:32658624 A G 0.96 1.34 2.36E-04 1.24 6p21.32 rs31350026:32668439 C A 1.00 1.35 1.74E-04 1.23
a SNP position according to NCBI genome build 37 (Hg19)
bGeno=genotyped, SNP, INFO, Rsq is the average across imputation batches. c Frequency of the effect allele.
North America South America
P OR P OR P
3.04E-05 0.93 3.39E-01 0.52 0.56 0.84 1.75E-07 0.36 2.49E-05 0.92 3.33E-01 0.52 0.56 0.84 1.30E-07 0.36 1.70E-05 0.94 4.34E-01 0.52 0.56 0.84 1.50E-07 0.26 1.70E-05 0.92 3.25E-01 0.52 0.56 0.84 1.08E-07 0.34 1.71E-05 0.92 3.25E-01 0.52 0.56 0.84 1.08E-07 0.34 1.79E-05 0.92 3.23E-01 0.52 0.56 0.84 1.12E-07 0.34 1.00E-04 0.89 1.45E-01 0.48 0.52 0.84 2.93E-07 0.66 5.41E-05 0.91 2.67E-01 0.51 0.55 0.84 2.29E-07 0.47 1.45E-05 0.92 3.16E-01 0.52 0.56 0.84 6.23E-08 0.34 1.49E-05 0.94 4.31E-01 0.52 0.56 0.84 9.17E-08 0.26 8.43E-05 0.89 1.42E-01 0.48 0.52 0.84 1.78E-07 0.66 1.51E-05 0.92 3.14E-01 0.52 0.56 0.84 6.41E-08 0.34 2.08E-05 0.92 3.20E-01 0.52 0.56 0.84 8.93E-08 0.35 2.26E-05 0.92 3.05E-01 0.51 0.55 0.84 1.66E-07 0.36 7.99E-05 0.89 1.52E-01 0.48 0.52 0.84 1.70E-07 0.63 2.50E-05 0.94 4.20E-01 0.52 0.56 0.84 1.20E-07 0.29 2.51E-05 0.92 3.04E-01 0.52 0.56 0.84 8.30E-08 0.38 2.47E-05 0.94 4.19E-01 0.52 0.56 0.84 1.23E-07 0.29 2.29E-05 1.07 4.21E-01 0.48 0.44 1.19 1.28E-07 0.28 2.57E-05 0.92 3.01E-01 0.52 0.56 0.84 8.99E-08 0.38 2.56E-05 0.92 3.19E-01 0.52 0.56 0.84 9.66E-08 0.36 2.46E-05 0.92 3.17E-01 0.52 0.56 0.84 9.96E-08 0.36 3.14E-05 0.93 3.36E-01 0.51 0.54 0.84 2.14E-07 0.36 2.32E-05 0.94 4.56E-01 0.52 0.56 0.84 1.53E-07 0.26 2.28E-05 0.95 4.80E-01 0.52 0.56 0.84 1.81E-07 0.24 2.84E-05 0.93 3.49E-01 0.51 0.54 0.84 2.10E-07 0.34 1.98E-05 0.95 4.95E-01 0.52 0.56 0.84 1.52E-07 0.23 7.31E-05 0.94 4.63E-01 0.53 0.56 0.84 3.19E-07 0.31 1.90E-05 0.93 3.55E-01 0.52 0.56 0.84 1.04E-07 0.31 1.92E-05 0.93 3.55E-01 0.52 0.56 0.84 1.06E-07 0.32 1.93E-05 0.93 3.57E-01 0.52 0.56 0.84 1.08E-07 0.31 1.95E-05 0.93 3.62E-01 0.52 0.56 0.84 1.11E-07 0.31 2.26E-05 0.94 4.42E-01 0.52 0.55 0.84 1.56E-07 0.26 6.43E-05 0.92 2.78E-01 0.46 0.50 0.85 3.86E-07 0.43 2.13E-05 0.94 4.42E-01 0.52 0.56 0.84 1.78E-07 0.26 3.00E-05 0.93 3.33E-01 0.48 0.52 0.84 2.14E-07 0.33 1.85E-05 0.91 2.40E-01 0.49 0.53 0.84 6.71E-08 0.39 1.59E-05 0.96 5.99E-01 0.52 0.56 0.84 1.75E-07 0.17 1.74E-05 1.05 5.49E-01 0.47 0.43 1.19 2.53E-07 0.20 6.56E-04 1.19 3.16E-02 0.37 0.34 1.19 2.18E-07 0.99 9.43E-04 1.19 2.61E-02 0.37 0.34 1.19 2.10E-07 1.00 6.03E-07 0.91 2.44E-01 0.53 0.57 0.84 6.54E-08 0.12 7.38E-07 0.91 2.37E-01 0.53 0.57 0.84 6.56E-08 0.13
Meta-analysisd
Frq.c
cases
Frq.c
7.39E-07 0.91 2.21E-01 0.53 0.57 0.84 6.24E-08 0.13 3.53E-05 1.09 2.75E-01 0.49 0.45 1.18 3.53E-07 0.37 6.57E-05 1.11 1.63E-01 0.48 0.44 1.18 3.16E-07 0.56 2.11E-05 1.05 5.06E-01 0.48 0.45 1.18 2.08E-07 0.19 2.21E-05 1.14 8.24E-02 0.47 0.43 1.19 8.00E-08 0.56 3.43E-05 1.08 2.97E-01 0.48 0.44 1.19 1.31E-07 0.36 1.24E-05 1.08 3.09E-01 0.48 0.44 1.19 5.48E-08 0.28 1.88E-05 1.10 2.16E-01 0.48 0.44 1.19 5.74E-08 0.40 1.96E-05 1.11 1.83E-01 0.48 0.44 1.19 5.83E-08 0.45 7.82E-05 1.38 8.63E-04 0.29 0.25 1.21 7.42E-08 0.20 3.06E-03 1.35 5.45E-04 0.36 0.32 1.20 2.55E-07 0.31 1.93E-03 1.33 1.01E-03 0.37 0.32 1.20 1.68E-07 0.41 2.22E-03 1.32 1.31E-03 0.37 0.32 1.20 1.74E-07 0.46 3.21E-03 1.35 3.66E-04 0.39 0.34 1.19 1.65E-07 0.29 3.20E-04 1.23 1.11E-01 0.12 0.10 1.31 2.28E-07 0.88 2.17E-04 1.28 6.35E-02 0.12 0.10 1.32 1.23E-07 0.93 2.24E-04 1.28 5.87E-02 0.12 0.10 1.32 1.20E-07 0.94 8.49E-05 1.21 1.18E-01 0.13 0.11 1.31 7.12E-08 0.77 9.29E-05 1.28 4.80E-02 0.14 0.11 1.31 6.82E-08 0.88 9.23E-05 1.27 4.88E-02 0.13 0.11 1.31 6.77E-08 0.88 3.08E-04 1.21 9.60E-02 0.16 0.14 1.29 5.97E-08 0.85 3.24E-04 1.29 6.27E-02 0.12 0.10 1.31 1.68E-07 0.98 9.07E-04 1.03 9.31E-01 0.03 0.02 1.71 1.05E-07 0.18 1.62E-02 1.07 4.30E-01 0.39 0.36 1.19 4.28E-07 0.09 1.60E-02 1.07 3.82E-01 0.39 0.36 1.19 3.47E-07 0.09 3.50E-04 1.10 2.72E-01 0.53 0.50 1.20 3.08E-07 0.53 3.02E-04 1.09 3.32E-01 0.55 0.51 1.20 4.20E-07 0.46 1.56E-04 1.06 4.82E-01 0.56 0.53 1.20 2.77E-07 0.29 1.18E-02 1.44 4.24E-02 0.11 0.07 1.37 2.49E-07 0.02 1.21E-02 1.37 8.64E-02 0.11 0.07 1.35 4.47E-07 0.04 4.30E-03 1.46 3.73E-02 0.10 0.07 1.40 6.62E-08 0.05 1.68E-04 1.23 4.42E-02 0.21 0.17 1.25 4.59E-07 0.94 4.24E-04 1.01 9.20E-01 0.52 0.48 1.19 2.05E-07 0.04 2.10E-02 1.26 1.24E-02 0.77 0.73 1.23 4.21E-07 0.24 3.37E-05 1.10 2.98E-01 0.26 0.22 1.25 1.03E-07 0.29 1.69E-02 0.80 1.57E-02 0.25 0.29 0.82 3.60E-07 0.27 8.51E-03 1.15 1.35E-01 0.79 0.76 1.24 4.65E-07 0.14 5.45E-04 1.04 6.87E-01 0.75 0.72 1.23 2.83E-07 0.06 6.71E-03 1.22 2.74E-02 0.68 0.64 1.24 6.11E-08 0.36 8.98E-04 1.19 9.29E-02 0.82 0.80 1.26 2.73E-07 0.63 1.35E-03 1.23 5.00E-02 0.84 0.81 1.27 1.71E-07 0.64
