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Poniewaz˙ w Europie ros´liny z rodzaju Forsythia nie sa˛ znane jako tradycyjne ros´liny lecznicze ani jadalne, ich zastosowanie jako materiału do wytwarzania

W dokumencie [2007/Nr 1] Bromatologia 1/2007 (Stron 53-57)

leko´w lub suplemento´w diety byłoby moz˙liwe dopiero po przeprowadzeniu

odpowiednich badan´ farmakologicznych w celu okres´lenia stosunku korzys´ci do

ewentualnego ryzyka ich stosowania a conajmniej wykazania braku efekto´w

toksycznych.

M. T o k a r, B. K l i m e k

FORSYTHIA PLANTS AS A SOURCE OF NATURAL ANTIOXIDANTS AND PHYTOESTROGENS

PIS

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MIENNICTWO

1. Kim K.J.: Molecular phylogeny of Forsythia (Oleaceae) based on chloroplast DNA variation. Plant. Syst. Evol., 1999; 218(1-2): 113-123. – 2. Seneta W., Dolatowski J.: Dendrologia. PWN, Warszawa, 2000; 462-465. – 3. Strzelecka H., Kowalski J.: Encyklopedia zielarstwa i ziołolecznictwa. PWN, Warszawa, 2000; 146-148. – 4. Hegi G.: Illustrierte Flora von Mittel-Europa. Bd. V/3, Lehmanns, München, 1926. – 5. Rouf A.S.S., Ozaki Y., Rashid M.A., Rui J.: Dammarane derivatives from the dried fruits of Forsythia suspensa. Phytochemistry 2001; 56: 815-818. – 6. Kitagawa S., Tsukamoto H., Hisada S., Nishibe S.: Studies on the Chinese Crude Drud „Forsythiae Fructus”. VII. A new caffeoyl glycoside from Forsythia viridissima. Chem. Pharm. Bull. 1984; 32(3): 1209-1213. – 7. Japanese Pharmacopoeia, 14thed, Ministry of Health and Welfare, Tokio 2002; Official Monographs for Part II, p. 920. – 8. Klimek B., Tokar M.: Biologically active compounds from the flowers of Forsythia suspensa Vahl. Acta Polon. Pharm., 1998; 55(6): 499-504. – 9. Ozaki Y., Rui J., Tang Y.T.: Antiinflammatory effect of Forsythia suspensa Vahl and its active principle. Biol. Pharm. Bull. 2000; 23(3): 365-367. – 10. Iwakami S., Wu J.B., Ebizuka Y., Sankawa U.: Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans, and sesquiterpenes. Chem.Pharm.Bull. 1992; 40(5):1196-1198.

11. Kumazawa N., Ohta S., Ishizuka O., Sakurai N., Kamogawa A., Shinoda M.: Protective effects of various methanol extracts of crude drugs on experimental hepatic injury induced by carbon tetrachloride in rats. Yakugaku Zasshi 1990; 110(12): 950-957, PMID; 2074541. – 12. Nikaido T., Ohmoto T., Kinoshita T., Sankawa U., Nishibe S., Hisada S.: Ihibition of cyclic AMP phosphodiesterase by lignans. Chem. Pharm. Bull. 1981; 29(12): 3586-3592. – 13. Harborne J.B., Green P.S.: A chemotaxonomic survey of flavonoids in leaves of the Oleaceae. Bot. J. Linn. Soc., 1980; 81: 155-167. – 14. Naghski J., Porter W.L., Couch J.F.: Isolation of rutin from two varieties of Forsythia. J. Am. Chem. Soc., 1947; 69: 572-573. – 15. Plouvier V., Sosa A.: Biochemical study of the flowers of various species of Forsythia (family Oleaceae). Bull. Soc. Chim. Biol., 1948; 30: 273-278, CA 42:8885f. – 16. Olechnowicz-Ste˛pien´

W.: Kwiaty forsycji jako z´ro´dło rutyny. Acta Pol. Pharm., 1957; 14(1): 33-40. – 17. Olechnowicz-Ste˛pien´ W.: Przyczynek do badan´ nad metabolizmem rutyny w kwiatach Forsythia sp. Acta Pol. Pharm., 1960; 17(2): 131-138. – 18. Klimek B., Tokar M.: Oznaczenia rutyny metoda˛ HPLC w kwiatach i lis´ciach forsycji – Forsythia species. Herba Polonica, 2000; 46(4): 261-266. – 19. Toker G., Türköz S., Erdemoglu N.: High performance liguid chromatographic analysis of rutin in plants I. Pharmazie, 1998; 53(7): 494-495. – 20. Temizer A., Kir S., Toker G., Baykal T., Sener B.: Differential pulse polarographic determination of flavonoids, I: Total flavonoids in Forsythia viridissima Lindl. Arch. Pharm. (Wein-heim), 1989; 322: 79-81.

21. S

´

wie˛s J., Robak J., Da˛browski L., Duniec Z., Michalska Z., Gryglewski R.J.: Antiaggregatory effects of flavonoids in vivo and their influence on lipoxygenase and cyclooxygenase in vitro. Pol. J. Pharmacol. Pharm., 1984; 36(5): 455-463. – 22. Galvez J., Cruz T., Crespo E., Ocete M.A., Lorente M.D., Sanchez de Medina F., Zarzuelo A.O.: Rutoside as mucosal protective in acetic acid-induced rat colitis. Planta Medica, 1997; 63(5): 409-414. – 23. Guardia T., Rotelli A.E., Juarez A.O., Pelzer L.E.: Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat. Farmaco., 2001; 56(9): 683-687. – 24. Cruz T., Galvez J., Ocete M.A., Crespo M.E., Sanchez de Medina L.H., Zarzuelo A.O.: Oral administration of rutoside can ameliorate inflammatory bowel disease in rats. Life Science, 1998; 67(9): 687-695. – 25. Lee M.H., Lin R.D., Shen L.Y., Yang L.L., Yen K.Y., Hou W.C.: Monoamine oxidase B and free radical scavenging activities of natural flavonoids in Melastoma candidum D. Don. J. Agric. Food Chem., 2001; 49(11): 5551-5555. – 26. Burda S., Oleszek W.: Antioxidant and antiviral activities of flavonoids. J. Agric. Food Chem., 2001; 49(6): 2774-2779. – 27. Grinberg L.N., Rachmilewitz E.A., Newmark H.: Protective effects of rutin against hemoglobin oxidation. Biochem. Pharmacol., 1994; 48(4): 643-649. – 28. Deschner E.E., Ruperto J., Wong G., Newmark H.L.: Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis, 1991; 12: 1193-1196. – 29. Gryglewski R.J., Korbut R., Robak J., S

´

wie˛s J.: On the mechanism of antithrombotic action of flavonoids. Biochem. Pharmcol., 1987; 36(3): 317-322. – 30. Boyle S.P., Dobson V.L., Duthie S.J., Hinselwood D.C., Kyle J.A., Collins A.R.: Bioavailability and efficiency of rutin as an antioxidant: a human supplementation study. Eur. J. Clin. Nutr., 2000; 54: 774-782.

31. Javernik S., Kreft S., Strukelj B., Vrecer F.: Oxidation of lovastatin in the solid state and its stabilization with natural antioxidants. Pharmazie, 2001; 56(9): 738-740. – 32. Zhao C., Shi Y., Lin W., Wang W., Jia Z., Yao S., Fan B., Zheng R.: Fast repair of the radical cations of dCMP and poly C by quercetin and rutin. Mutagenesis, 2001; 16: 271-275. – 33. Cos P., Calomme M., Sindambiwe J.B., De Bruyne T., Cimanga K., Pieters L., Vlietinck A.J., Vander Berghe D.: Cytotoxicity and lipid peroxidation-inhibiting activity of flavonoids. Planta Medica, 2001; 67(6): 515-519. – 34. Kitagawa S., Hisada S., Nishibe S.: Phenolic compounds from Forsythia leaves. Phytochemistry, 1984; 23(8): 1635-1636. – 35. Endo K., Takahaski K., Abe T., Hikino H.: Structure of forsythoside B, an antibacterial principle of Forsythia koreana stems. Heterocycles, 1982; 19(2): 261-264. – 36. Klimek B., Tokar M.: Isolation and quantitative determination of lignans and phenylethanoids in flowers and leaves of Forsythia sp. VI Ogo´lnopolska Konferencja Naukowa na temat: Zastosowanie metod chromatograficz-nych w badaniach fitochemiczchromatograficz-nych i biomedyczchromatograficz-nych, P-15, Lublin, 1997. – 37. Klimek B.: Verbascoside in the flowers of some Verbascum species. Acta Polon. Pharm., 1991; 48(3-4): 51-54. – 38. Hansel R., Sticher O., Steinegger E.: Pharmacognosie-Phytopharmazie. Springer-Verlag, Berlin-Heidelberg, 1999. – 39. Xiong Q., Kadota S., Tani T., Namba T.: Antioxidative effects of phenylethanoids from Cistanche deserticola. Biol. Pharm. Bull., 1996; 19(12): 1580-1585. – 40. Li J., Wang P.F., Zheng R., Liu Z.M., Jia Z.: Protection of phenylpropanoid glycosides from Pedicularis against oxidative hemolysis in vitro. Planta Medica, 1993; 59(4): 315-317.

41. Xiong Q., Hase K., Tezuka Y., Tani T., Namba T., Kadota S.: Hepatoprotective activity of phenylethanoids from Cistanche deserticola. Planta Medica, 1998; 64(2): 120-125. – 42. Xiong Q., Hase K., Tezuka Y., Namba T., Kadota S.: Acteoside inhibits apoptosis in D-galactosamine and lipopolysac-charide – induced liver injury. Life Science, 1999; 65(4): 421-430. – 43. Seidel V., Verholle M., Malard Y., Tillequin F., Fruchart J.C., Duriez P., Bailleul F., Teissier E.: Phenylpropanoids from Ballota nigra L. inhibit in vitro LDL peroxidation. Phytother. Res., 2000; 14(2): 93-98. – 44. Wang P., Kang J., Zheng R., Yang Z., Lu J., Gao J., Jia Z.: Scavenging effects of phenylpropanoid glycosides from Pedicularis on superoxide anion and hydroxyl radical by the spin trapping method. Biochem. Pharmacol., 1996; 51(5): 687-691. – 45. Heilmann J., Calis I., Kirmizibelimez H., Schühly W., Harput S., Sticher O.: Radical scavenger activity of phenylethanoid glycosides in FMLP stimulated human polymorphonuclear leukocytes: structure – activity relationships. Planta Medica, 2000; 66(8): 746-748. – 46. Liao F., Zheng

R.L., Gao J.J., Jia Z.J.: Retardation of skeletal muscle fatique by the two phenylpropanoid glycosides: verbascoside and martynoside from Pedicularis plicata maxim. Phytother. Res., 1999; 13(7): 621-623. – 47. Zhou B.N., Bahler B.D., Hofmann G.A., Mattern M.R., Johnson R.K., Kingston D.G.I.: Phenylethanoid glycosides from Digitalis purpurea and Pestemon linarioides with PKCα – inhibitory activity. J. Nat. Prod., 1998; 61(11): 1410-1412. – 48. Pettit G.R., Numata A., Takemura T., Ode R.H., Narula A.S., Schmidt J.M., Cragg G.M., Pase C.P.: Antineoplastic agents, 107. Isolation of acteoside and isoacteoside from Castilleja linariaefolia. J. Nat. Prod., 1990; 53(2): 456-458. – 49. Klimek B., Ste˛pien´ H.: Effect of some constituents of mullein (Verbascum sp.) on proliferation of rat splenocytes in vitro. Eur. J. Pharm. Sci., 1994; 2(1,2): 123. – 50. Li J., Zheng Y., Zhou H., Su B., Zheng R.: Differentation of human gastric adenocarcinoma cell line MGc 80-3 induced by verbascoside. Planta Medica, 1997; 63(6): 499-502.

51. Inoue M., Sakuma Z., Ogihara Y., Saracoglu I.: Induction of apoptotic cell death in HL-60 cells by acteoside, a pheylpropanoid glycoside. Biol. Pharm. Bull., 1998; 21(1): 81-83. – 52. Murai M., Tamayama Y., Nishibe S.: Phenylethanoids in the herb of Plantago lanceolata and inhibitory effect on arachidonic acid – induced mouse ear edema. Planta Medica, 1995; 61(5): 479-480. – 53. Hayashi K., Nagamatsu T., Ito M., Hattori T., Suzuki Y.: Acteoside, a component of Stachys sieboldii MIQ, may be a prommising antinephritic agent (3): effect of acteoside on expression of intercellural adhesion molecule-1 in experimental nephritic glomeruli in rats and cultured endothelial cells. Jpn. J. Pharmacol., 1996; 70(2): 157-168. – 54. Wong I.Y., Huang Y., He Z.D., Lau C.W., Chen Z.Y.: Relaxing effects of Ligustrum purpurascens extract and purified acteoside in rat aortic rings. Planta Medica, 2001; 67(4): 317-321. – 55. Seya K., Endo K., Hikino H.: Structure of rengyosides A, B and C, three glucosides of Forsythia suspensa fruits. Phytochemistry, 1989; 28(5): 1495-1498. – 56. Tokar M., Klimek B.: Isolation and identification of biologically active compounds from Forsythia viridissima flowers. Acta Polon. Pharm., 2004; 61(3): 191-197. – 57. Tokar M., Klimek B.: The content of lignan glycosides in Forsythia flowers and leaves. Acta Polon. Pharm., 2004; 61(4): 273-278. – 58. Vlietinck A.J., Bruyne T.D., Apers S., Pieters L.A.: Plant-derived compounds for chemotherapy of human immunodeficiency virus (HIV) infection. Planta Medica, 1998; 64(2): 97-109. – 59. Li L.N.: Biologically active components from traditional Chinese medicines. Pure App. Chem., 1998; 70(3): 547-554. – 60. Jeng K.C.G., Hou R.C.W.: Sesamin and sesaminol: nature’s therapeutic lignans. Current Enzyme Inhibition, 2005; 1 (1): 11-20. 61. Nishibe S., Deyama T., Hayashi K., Kawamura T., Tanaka T., Sakai E., Heinonen S., Adlercreutz H.: Uses of Forsythia leaves as phytoestrogen source. 1stInternational Conference on Polyphenols and Health, Abstracts books, France 2003; P59. – 62. Chiba M., Tsukamoto H., Hisada S., Nishibe S.: Studies on the Chinese crude drug „Forsythiae fructus” (IV). On the constituents of fruits of Forsythia koreana and Forsythiae fructus from Korea on the market. Shoyakugaku Zasshi, 1979; 33(3): 150-154. – 63. Chen Y., Xiang J., Xu M., Tao L., Gu W.: Studies on chemical constituents from Forsythia suspensa. Zhongguo Zhong Yao Zazhi, 1999; 24(5): 296-319, CA 132:47510. – 64. Moon C.K., Park K.S., Lee S.H., Ha B.J., Iee B.G.: Effects of antitumor polysaccharides from forsythia corea on the immune function. Arch. Pharmacal Res., 1985; 8(1): 31-38, CA 103:153483e. – 65. Bhathena S.J., Velasquez M.T.: Beneficial role of dietary phytoestrogens in obesity and diabetes. Am. J. Clin. Nutr., 2002; 76: 1191-1201. – 66. Heinonen S., Nurmi T., Liukkonen K., Poutanen K., Wahala K., Deyama T., Nishibe S., Adlercreutz H.: In vitro metabolism of plants lignans: new precursors of mammalian lignans enterolactone and enterodiol. J. Agri. Food Chem. 2001; 49(7): 3178-3186.

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