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Trans fatty acids increase the instability of atherosclerotic plaques

The study of Naruszewicz et al. has shown that trans fatty acids cause a significant increase in the secretion of metalloproteinase -9, reactive oxygen species, interleukin -6,

and tumor necrosis factor. It was concluded that trans fatty acids may contribute to the destruction of endothelial integ-rity and to increased risk of plaque rupture [69].

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R O C Z N I K I P O M O R S K I E J A K A D E M I I M E D Y C Z N E J W S Z C Z E C I N I E 2010, 56, 3, 39–49

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